{"id":"W2152469629","doi":"10.1371/journal.pone.0098431","title":"A Loss of Function Analysis of Host Factors Influencing Vaccinia virus Replication by RNA Interference","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Bacteriophages and microbial interactions","field":"Environmental Science","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Research in Immunology and Cancer; Université de Montréal","funders":"Biotechnology and Biological Sciences Research Council; Engineering and Physical Sciences Research Council; Wellcome Trust","keywords":"Biology; Viral replication; RNA interference; Vaccinia; Cell biology; Virus; Gene silencing; Viral life cycle; DNA replication; RNA; Virology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0000909399,0.00007318151,0.0001980057,0.00006863751,0.0000339502,0.00000908175,0.0001213258,0.0000406099,0.001456806],"category_scores_gemma":[0.00005866498,0.00006854601,0.00006463309,0.0003808174,0.00004282732,0.0001800022,0.00006456036,0.00006778465,0.0000403009],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005894392,"about_ca_system_score_gemma":0.000002389712,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001939484,"about_ca_topic_score_gemma":0.0003433356,"domain_scores_codex":[0.9993101,0.00002980767,0.0002543327,0.0002058664,0.0001106426,0.00008922308],"domain_scores_gemma":[0.9993274,0.00004167835,0.0002275183,0.000344452,0.00002320669,0.00003578838],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000216838,0.0002792509,0.04006264,0.000009493176,0.0002124897,1.952001e-8,0.0002645559,0.0000180819,0.9585049,0.000004367237,0.00004099217,0.0005814807],"study_design_scores_gemma":[0.00004455616,0.00008632243,0.423361,0.00001952884,0.0003409114,5.463993e-8,0.00002771197,0.0004055422,0.5756092,0.000004624811,0.00005349028,0.00004702249],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998423,0.00000635957,0.0008149367,0.00002795108,0.00001666772,0.0000726037,0.00003939951,0.00001370193,0.0005853307],"genre_scores_gemma":[0.9995959,0.00001625763,0.0001563472,0.00003622855,0.00000636705,0.000004750222,0.00003178943,0.000005647999,0.0001466784],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3832984,"threshold_uncertainty_score":0.999456,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01992941587380029,"score_gpt":0.2255342625719841,"score_spread":0.2056048466981838,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}