{"id":"W2152469629","doi":"10.1371/journal.pone.0098431","title":"A Loss of Function Analysis of Host Factors Influencing Vaccinia virus Replication by RNA Interference","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Bacteriophages and microbial interactions","field":"Environmental Science","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Research in Immunology and Cancer; Université de Montréal","funders":"Biotechnology and Biological Sciences Research Council; Engineering and Physical Sciences Research Council; Wellcome Trust","keywords":"Biology; Viral replication; RNA interference; Vaccinia; Cell biology; Virus; Gene silencing; Viral life cycle; DNA replication; RNA; Virology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002887741,0.0005910756,0.0003966863,0.0003892159,0.0001917027,0.000349883,0.000289812,0.0002883732,0.001531648],"category_scores_gemma":[0.0002203843,0.0002234185,0.0004479478,0.0002317313,0.0002479094,0.0001423488,0.0001814003,0.0005354821,0.0003538904],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003118318,"about_ca_system_score_gemma":0.0002291453,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004979204,"about_ca_topic_score_gemma":0.0008948028,"domain_scores_codex":[0.9997074,0.00003974403,0.00003872319,0.00007350999,0.00008757937,0.00005300769],"domain_scores_gemma":[0.9998093,0.0000901103,0.00003407036,0.00002469755,0.00001660333,0.00002523529],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003275073,0.00001664253,0.00008059573,0.00001867259,0.000005278144,0.00002720857,0.000004776585,0.00004528985,0.9988322,0.00006569782,0.00002399287,0.0008470815],"study_design_scores_gemma":[0.00001931396,0.0004256995,0.003644526,0.000004612926,0.0000476405,0.0002077358,0.00001417645,0.002276382,0.9898049,0.00004173399,0.003506641,0.000006604744],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9814335,0.001596152,0.01128007,0.0001318257,0.00006741381,0.0001638583,0.002138828,0.0003008882,0.002887612],"genre_scores_gemma":[0.9830182,0.001238827,0.008902255,0.00009067186,0.00001321108,0.0001744467,0.002745683,0.0001069189,0.003709859],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001531648,"threshold_uncertainty_score":0.005123913,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01992941587380029,"score_gpt":0.2255342625719841,"score_spread":0.2056048466981838,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}