{"id":"W2152550058","doi":"10.1093/carcin/bgn167","title":"Loss of MKP3 mediated by oxidative stress enhances tumorigenicity and chemoresistance of ovarian cancer cells","year":2008,"lang":"en","type":"article","venue":"Carcinogenesis","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":214,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"University of Hong Kong; Ministry of Education, Culture, Sports, Science and Technology; University of Ottawa","keywords":"Ovarian cancer; Kinase; Cancer research; MAPK/ERK pathway; Biology; Cell growth; Cancer cell; Cancer; Cell biology; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006947562,0.0001656306,0.0002775958,0.00002659226,0.000052066,0.000002812165,0.0001969259,0.0000945501,0.00002748606],"category_scores_gemma":[0.00006431219,0.0001599976,0.00005992284,0.0001302968,0.0003850612,0.000005628131,0.00009301161,0.00003681782,6.085507e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001225162,"about_ca_system_score_gemma":0.0001133016,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000604784,"about_ca_topic_score_gemma":0.00009158641,"domain_scores_codex":[0.9990177,0.00004732777,0.0002577747,0.0003282089,0.0001591986,0.0001897448],"domain_scores_gemma":[0.9992054,0.00002593937,0.000219398,0.0002945234,0.0001768356,0.00007792097],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001339426,0.0000537205,0.04037394,0.00009536439,0.00006560115,0.000004165269,0.00006281924,0.000006245268,0.95808,0.0000212458,0.0009382147,0.0001647172],"study_design_scores_gemma":[0.0004048186,0.00009102021,0.02698833,0.00002690962,0.00003074191,0.000003702369,0.00003144492,0.000003231642,0.9719836,0.000006917151,0.0002728459,0.0001564243],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9462616,0.05137422,0.0001998315,0.0000261382,0.00005208466,0.0001677744,0.001881772,0.000005415697,0.00003119082],"genre_scores_gemma":[0.9951125,0.004132499,0.0003664162,0.00003500534,0.00004808233,0.00003724534,0.0001738716,0.00001786397,0.00007649128],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04885095,"threshold_uncertainty_score":0.6524515,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00860934186035597,"score_gpt":0.2274322173339891,"score_spread":0.2188228754736331,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}