{"id":"W2152550058","doi":"10.1093/carcin/bgn167","title":"Loss of MKP3 mediated by oxidative stress enhances tumorigenicity and chemoresistance of ovarian cancer cells","year":2008,"lang":"en","type":"article","venue":"Carcinogenesis","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":214,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"University of Hong Kong; Ministry of Education, Culture, Sports, Science and Technology; University of Ottawa","keywords":"Ovarian cancer; Kinase; Cancer research; MAPK/ERK pathway; Biology; Cell growth; Cancer cell; Cancer; Cell biology; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007792734,0.0002461559,0.0002317021,0.0001884198,0.0001489151,0.0002273133,0.0001205047,0.0002036457,0.0009032553],"category_scores_gemma":[0.00007877565,0.0001248542,0.0002412813,0.0001772854,0.0002045676,0.0001566156,0.0002145319,0.0005647113,0.0001953376],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002548477,"about_ca_system_score_gemma":0.0002070608,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006747398,"about_ca_topic_score_gemma":0.0007866754,"domain_scores_codex":[0.999918,0.000009819752,0.000008601251,0.00001262563,0.00002591323,0.00002508332],"domain_scores_gemma":[0.9999496,0.000006771525,0.00001542089,0.000006780099,0.000005531171,0.00001599782],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009536073,0.00002562593,0.0002590214,0.00002925479,0.000005851037,0.00005931029,0.00001611421,0.00005851888,0.9984938,0.00008329998,0.00004680363,0.0008270661],"study_design_scores_gemma":[0.00002869222,0.0002675293,0.009060035,0.000004303269,0.00002398473,0.0005011361,0.00002902421,0.001563639,0.9859574,0.00009645238,0.002462865,0.000005017821],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968079,0.0007408204,0.00126845,0.000102436,0.00001863972,0.00001881137,0.0002246525,0.00008480556,0.0007334919],"genre_scores_gemma":[0.9984245,0.0002483383,0.000407374,0.00002905497,0.000003305982,0.00001531983,0.0001925455,0.000007531986,0.000672045],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009032553,"threshold_uncertainty_score":0.003021657,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00860934186035597,"score_gpt":0.2274322173339891,"score_spread":0.2188228754736331,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}