{"id":"W2152573097","doi":"10.1096/fj.06-7691com","title":"Biphenyl 2,3′,4,5′,6‐pentakisphosphate, a novel inositol polyphosphate surrogate, modulates Ca <sup>2+</sup> responses in rat hepatocytes","year":2007,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Fiducie de Recherche sur la Foret des Cantons-de-l'Est; Wellcome Trust","keywords":"Polyphosphate; Chemistry; Inositol; Phosphatase; Stereochemistry; Biphenyl; Substrate (aquarium); Inositol phosphate; Phosphate; Biochemistry; Enzyme; Receptor; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007093622,0.0002618855,0.0001343676,0.00008743377,0.00005369069,0.0001519678,0.0001339836,0.000235837,0.000963049],"category_scores_gemma":[0.00007229148,0.0001102576,0.0001004134,0.0001085591,0.0001016026,0.0001267582,0.00007139961,0.0002821217,0.0002891876],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001341034,"about_ca_system_score_gemma":0.0001458816,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005078655,"about_ca_topic_score_gemma":0.0006125856,"domain_scores_codex":[0.9999371,0.00001288787,0.000006194717,0.00001106263,0.00001711438,0.0000156203],"domain_scores_gemma":[0.9999496,0.000009701251,0.00001727445,0.000004379958,0.000006587724,0.00001252593],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000115466,0.000009402995,0.0000266746,0.00001620167,0.000001201004,0.00002011878,0.000001956849,0.00004689116,0.9993209,0.00001594498,0.00001235971,0.0004129674],"study_design_scores_gemma":[0.00001051971,0.0002872575,0.00062656,9.022535e-7,0.000004684262,0.00005342663,0.000004159539,0.0002069624,0.9984286,0.000005669551,0.0003699304,0.00000142796],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946406,0.001371039,0.002190998,0.00006260544,0.00002253192,0.00001725017,0.0002731717,0.00007281255,0.001348956],"genre_scores_gemma":[0.9952239,0.0009358196,0.001881276,0.00006608535,0.000008565708,0.0000206771,0.0002881814,0.00001235232,0.001563259],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000963049,"threshold_uncertainty_score":0.00322175,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01415613275638893,"score_gpt":0.2553985166151616,"score_spread":0.2412423838587726,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}