{"id":"W2152573344","doi":"10.1196/annals.1361.048","title":"Control of Type 1 Autoimmune Diabetes by Naturally Occurring CD4+CD25+Regulatory T Lymphocytes in Neonatal NOD Mice","year":2005,"lang":"en","type":"review","venue":"Annals of the New York Academy of Sciences","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"IL-2 receptor; NOD mice; Nod; Interleukin 21; Biology; T cell; Pancreatic islets; Cytokine; Regulatory T cell; Immune system; Autoimmunity; Immunology; Islet; Endocrinology; Insulin; Diabetes mellitus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001214497,0.0005081256,0.001486346,0.0002021523,0.0001255558,0.00003319949,0.002231623,0.0007456471,0.00002030775],"category_scores_gemma":[0.0003837926,0.0003694754,0.0007562176,0.0008773713,0.000943641,0.00003470574,0.0003619923,0.0004046667,0.000004065954],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002696567,"about_ca_system_score_gemma":0.0006031701,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008468497,"about_ca_topic_score_gemma":0.000002968912,"domain_scores_codex":[0.9966236,0.0002653283,0.001137157,0.0006591489,0.0006169425,0.0006977684],"domain_scores_gemma":[0.9980436,0.0002142012,0.001254466,0.0002811248,0.00009582443,0.0001108041],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009924779,0.0003535627,0.002779598,0.004092063,0.001601582,4.280182e-7,0.0004702139,0.00909339,0.01033211,0.0002552875,0.03815196,0.9327706],"study_design_scores_gemma":[0.0009936838,0.0002832499,0.0001965866,0.005930232,0.0003269954,0.00000217215,0.0002278305,0.0008653197,0.01712291,0.0001486765,0.9731604,0.0007419506],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1007791,0.8979319,7.23289e-7,0.000500551,0.00006309791,0.0003969004,0.0002112593,0.000009205312,0.0001072663],"genre_scores_gemma":[0.2369999,0.7613997,0.00009900529,0.0009324596,0.0001562536,0.00001360564,0.00004239856,0.00003990718,0.0003168079],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9350084,"threshold_uncertainty_score":0.9998757,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02522446376891333,"score_gpt":0.2995097382733515,"score_spread":0.2742852745044382,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}