{"id":"W2152623031","doi":"10.1139/cjc-2012-0221","title":"Enantioselective synthesis of 3-substituted tryptamines as core components of central nervous system drugs and indole natural products","year":2012,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Asymmetric Synthesis and Catalysis","field":"Chemistry","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Chemistry; Tryptamines; Indole test; Iminium; Enantioselective synthesis; Organic chemistry; Combinatorial chemistry; Stereochemistry; Catalysis; Tryptamine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002070699,0.000199473,0.0005719129,0.0001285914,0.00007079882,0.00001648613,0.0002945369,0.0001533217,0.00005763067],"category_scores_gemma":[0.0007807948,0.0001771264,0.000155721,0.0003396746,0.00019538,0.0001501628,0.00001883673,0.0002276965,9.257967e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002416015,"about_ca_system_score_gemma":0.0005609537,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001627938,"about_ca_topic_score_gemma":0.00004242283,"domain_scores_codex":[0.9985222,0.00001740275,0.0005898554,0.0001522952,0.0002990292,0.000419173],"domain_scores_gemma":[0.9979253,0.0001501077,0.0007805859,0.0002170749,0.00040171,0.0005251747],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009622222,0.00009680972,0.04498074,0.002069087,0.0006482836,0.00004837121,0.001204242,0.000004372888,0.9376602,0.00003190798,0.0002882712,0.01287146],"study_design_scores_gemma":[0.0002993383,0.000005515869,0.01306933,0.0005727121,0.0002181512,0.0004147901,0.002566998,0.00001783363,0.982421,0.000003395345,0.0002434253,0.0001674651],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914836,0.00402724,0.000001818444,0.00003691086,0.0001462533,0.0000341605,0.00007343007,0.000005546804,0.004191063],"genre_scores_gemma":[0.9993847,0.000026921,0.00008206674,0.00000405593,0.0003151903,0.000002175902,0.00001405885,0.00002058402,0.0001502187],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04476082,"threshold_uncertainty_score":0.7223004,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009116509522739038,"score_gpt":0.1923240608615316,"score_spread":0.1832075513387926,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}