{"id":"W2152624601","doi":"10.1128/iai.01442-06","title":"Induction of Monocyte Chemotactic Protein 1 in Colonic Epithelial Cells by <i>Entamoeba histolytica</i> Is Mediated via the Phosphatidylinositol 3-Kinase/p65 Pathway","year":2007,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Amoebic Infections and Treatments","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Canadian Association of Gastroenterology; McGill University","keywords":"Biology; Chemotaxis; Phosphatidylinositol; Entamoeba histolytica; Cell biology; Protein kinase A; Chemokine; Kinase; Monocyte; Signal transduction; Molecular biology; Protein kinase B; Mitogen-activated protein kinase; Inflammation; Biochemistry; Immunology; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004645997,0.0001653793,0.0002485464,0.000138739,0.0002114738,0.00001177908,0.00003904022,0.0001606565,0.0001326396],"category_scores_gemma":[0.00006707424,0.0001250048,0.00007460902,0.0004222374,0.0001619476,0.0001306547,0.0000322973,0.0004160714,0.00002904399],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002657931,"about_ca_system_score_gemma":0.0000808367,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006671685,"about_ca_topic_score_gemma":0.0002180653,"domain_scores_codex":[0.9989774,0.00009525571,0.0003748678,0.0001728386,0.0001632127,0.0002164069],"domain_scores_gemma":[0.9992618,0.00009756035,0.0001930614,0.0002630409,0.0001066606,0.00007789809],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009252403,0.003123801,0.06097177,0.0001375877,0.0002400334,0.00002168989,0.001438332,0.000002110379,0.9010802,0.00008095892,0.0004769315,0.03150132],"study_design_scores_gemma":[0.00286575,0.0007588772,0.0990466,0.00006330098,0.00008876884,0.0000738429,0.0001342913,0.0001532921,0.8890619,0.00008064513,0.007540099,0.0001326478],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967495,0.0001955313,0.0004277864,0.0002162844,0.0002735748,0.0008196615,0.00001530424,0.00004094169,0.001261463],"genre_scores_gemma":[0.9991273,0.0001725282,0.00004368071,0.0001676025,0.00003733019,0.00003786812,0.00003172733,0.00001556894,0.0003663842],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03807482,"threshold_uncertainty_score":0.999943,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009771835486804523,"score_gpt":0.2464345016325111,"score_spread":0.2366626661457066,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}