{"id":"W2152624601","doi":"10.1128/iai.01442-06","title":"Induction of Monocyte Chemotactic Protein 1 in Colonic Epithelial Cells by <i>Entamoeba histolytica</i> Is Mediated via the Phosphatidylinositol 3-Kinase/p65 Pathway","year":2007,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Amoebic Infections and Treatments","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Canadian Association of Gastroenterology; McGill University","keywords":"Biology; Chemotaxis; Phosphatidylinositol; Entamoeba histolytica; Cell biology; Protein kinase A; Chemokine; Kinase; Monocyte; Signal transduction; Molecular biology; Protein kinase B; Mitogen-activated protein kinase; Inflammation; Biochemistry; Immunology; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001171938,0.0003545658,0.0001902783,0.0001579832,0.0001419049,0.0002587556,0.00006573764,0.0001805265,0.0008222026],"category_scores_gemma":[0.00009291165,0.0001225337,0.0002177073,0.0001349294,0.0001702192,0.0001527704,0.0001856082,0.0004317003,0.0003282665],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002113716,"about_ca_system_score_gemma":0.0001581484,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003760413,"about_ca_topic_score_gemma":0.000571597,"domain_scores_codex":[0.9998635,0.00002935234,0.00001074496,0.00001509087,0.00003152655,0.0000498008],"domain_scores_gemma":[0.9999136,0.00001638977,0.00002492031,0.0000098225,0.00001174839,0.00002353367],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005618515,0.0000102188,0.0001368811,0.00003389434,0.000001264359,0.00004260609,0.000007005613,0.000007546092,0.9991845,0.00001280748,0.00001531815,0.0004915358],"study_design_scores_gemma":[0.00002437711,0.000554038,0.02411113,0.000009589474,0.00001102049,0.0004322653,0.00005800653,0.0004890979,0.9725122,0.00004273076,0.001750916,0.000004635345],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944344,0.002431951,0.001643825,0.0001227838,0.00003585625,0.00002133105,0.0002668111,0.00006356772,0.0009795623],"genre_scores_gemma":[0.9949186,0.001412182,0.002058489,0.00005881949,0.00001810101,0.00003066247,0.0004185752,0.000006600119,0.001077894],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008222026,"threshold_uncertainty_score":0.002750576,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009771835486804523,"score_gpt":0.2464345016325111,"score_spread":0.2366626661457066,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}