{"id":"W2152651181","doi":"10.4049/jimmunol.178.7.4373","title":"Bcl10 Controls TCR- and FcγR-Induced Actin Polymerization","year":2007,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; Ontario Institute for Cancer Research","funders":"Deutsche Krebshilfe; Schweizerische Akademie der Medizinischen Wissenschaften; Centre National de la Recherche Scientifique; Studienstiftung des Deutschen Volkes; Deutsche Forschungsgemeinschaft; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Cell biology; Phosphorylation; BCL10; Ionomycin; Biology; T-cell receptor; Actin; Jurkat cells; Chemistry; T cell; Immune system; Biochemistry; Immunology; Intracellular","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001492069,0.0003262006,0.0001333726,0.0001924195,0.0001576357,0.0004020251,0.000204194,0.0002705674,0.001577446],"category_scores_gemma":[0.0001839196,0.0001615091,0.0001239092,0.00009886269,0.0003139503,0.0001969391,0.0002190002,0.0004882893,0.0007694506],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005090066,"about_ca_system_score_gemma":0.0002003146,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006042695,"about_ca_topic_score_gemma":0.0008980006,"domain_scores_codex":[0.9998046,0.00003398654,0.00001155789,0.00003323878,0.00003908265,0.00007763794],"domain_scores_gemma":[0.9997367,0.0000548456,0.00008110116,0.00003160768,0.00001958445,0.00007606334],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001539001,0.00002153732,0.0001230609,0.00001295081,0.00000103791,0.0000305358,0.00000932377,0.00002638173,0.9988329,0.00005423649,0.00001997684,0.0007141035],"study_design_scores_gemma":[0.00002580623,0.0001161235,0.001628686,0.000003790083,0.000004809375,0.0001677081,0.00002289113,0.0007677818,0.9958594,0.0000386255,0.001361753,0.000002515467],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962412,0.0008351198,0.001485084,0.00006282512,0.00002046981,0.00001047724,0.0001060863,0.00007896879,0.001159805],"genre_scores_gemma":[0.997451,0.0003106853,0.0006380359,0.00001944426,0.000004679103,0.00001109456,0.0001408376,0.00002394279,0.001400366],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001577446,"threshold_uncertainty_score":0.005277038,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008898193397320507,"score_gpt":0.2387648568992186,"score_spread":0.2298666635018981,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}