{"id":"W2152651181","doi":"10.4049/jimmunol.178.7.4373","title":"Bcl10 Controls TCR- and FcγR-Induced Actin Polymerization","year":2007,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; Ontario Institute for Cancer Research","funders":"Deutsche Krebshilfe; Schweizerische Akademie der Medizinischen Wissenschaften; Centre National de la Recherche Scientifique; Studienstiftung des Deutschen Volkes; Deutsche Forschungsgemeinschaft; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Cell biology; Phosphorylation; BCL10; Ionomycin; Biology; T-cell receptor; Actin; Jurkat cells; Chemistry; T cell; Immune system; Biochemistry; Immunology; Intracellular","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001676385,0.000120101,0.0002729382,0.0001953137,0.0001966947,0.000009911962,0.0002214303,0.0002284823,0.0001332629],"category_scores_gemma":[0.0002771996,0.00007798849,0.00006300079,0.0001116609,0.0002004484,0.0001687542,0.00004969192,0.0004608555,0.00007298406],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003030644,"about_ca_system_score_gemma":0.00006340298,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003000572,"about_ca_topic_score_gemma":0.000007412999,"domain_scores_codex":[0.998616,0.0004604616,0.0005488736,0.00006669467,0.00003622323,0.0002717123],"domain_scores_gemma":[0.9985213,0.0005917347,0.0005621047,0.0001761144,0.0001363834,0.00001237646],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002539311,0.00002941686,0.0001363292,0.000002013349,0.0002613258,0.000005242165,0.0007912731,7.746494e-7,0.9593284,0.0005106642,0.00009912638,0.0362962],"study_design_scores_gemma":[0.002226796,0.0007847305,0.02729316,0.00002394173,0.000093708,0.002292028,0.001213973,0.000001731636,0.950798,0.0001477739,0.01502368,0.0001004414],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9863794,0.009506349,0.001207842,0.00135285,0.0008774881,0.0001091527,8.100457e-7,0.0000134872,0.0005525906],"genre_scores_gemma":[0.9985,0.0006999617,0.00003233125,0.0001866518,0.00006339115,7.033546e-7,0.000003984306,0.00001042782,0.0005024736],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03619576,"threshold_uncertainty_score":0.3180278,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008898193397320507,"score_gpt":0.2387648568992186,"score_spread":0.2298666635018981,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}