{"id":"W2152656428","doi":"10.1128/jvi.02798-06","title":"Human Immunodeficiency Virus Type 1 Protease Cleaves Procaspase 8 In Vivo","year":2007,"lang":"en","type":"article","venue":"Journal of Virology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":73,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; Burroughs Wellcome Fund","keywords":"Biology; Apoptosis; Protease; Virology; Programmed cell death; Caspase; Virus; CD8; Bystander effect; Immunology; Immune system; Enzyme; Genetics; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002660321,0.0003882904,0.0001754747,0.0002294951,0.0001255927,0.0003354294,0.0001915412,0.0003369533,0.00154247],"category_scores_gemma":[0.0003069323,0.0001720187,0.0002152946,0.00008492572,0.0001428956,0.0002675843,0.0001586922,0.0005876256,0.0006528047],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002390793,"about_ca_system_score_gemma":0.0001006798,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001139524,"about_ca_topic_score_gemma":0.0001035247,"domain_scores_codex":[0.9998462,0.00004650084,0.0000106347,0.00002749789,0.00003343458,0.00003563042],"domain_scores_gemma":[0.9998096,0.00007075255,0.0000402918,0.00003370376,0.000016805,0.00002896449],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002317115,0.00008942607,0.000641456,0.00004630443,0.00001255766,0.0001056289,0.0000122526,0.00007126065,0.9944911,0.0001096068,0.0001021437,0.004086471],"study_design_scores_gemma":[0.00006112185,0.0008162577,0.007530326,0.00000963632,0.00001835549,0.002223888,0.0000201404,0.001275164,0.9852201,0.0003805364,0.002439098,0.000005502965],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9913551,0.004199207,0.002747467,0.0001211701,0.00004699498,0.00002225399,0.0001585744,0.00004670858,0.001302487],"genre_scores_gemma":[0.9947548,0.001332629,0.001828733,0.00004882004,0.00003199331,0.00002265902,0.000446206,0.000009809432,0.001524371],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00154247,"threshold_uncertainty_score":0.005160093,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01863338185155253,"score_gpt":0.3093104179081768,"score_spread":0.2906770360566243,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}