{"id":"W2152685591","doi":"10.1021/jo048875+","title":"Phosphaadamantanes as Ligands for Palladium Catalyzed Cross-Coupling Chemistry:  Library Synthesis, Characterization, and Screening in the Suzuki Coupling of Alkyl Halides and Tosylates Containing β-Hydrogens with Boronic Acids and Alkylboranes","year":2004,"lang":"en","type":"article","venue":"The Journal of Organic Chemistry","topic":"Catalytic Cross-Coupling Reactions","field":"Chemistry","cited_by":85,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Chemistry; Phosphine; Halide; Alkyl; Palladium; Suzuki reaction; Ligand (biochemistry); Combinatorial chemistry; Boronic acid; Catalysis; Organic chemistry; Aryl; Medicinal chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006663355,0.000333849,0.0005304203,0.00003346441,0.0003394313,0.0002741859,0.0003826058,0.0001850541,0.00007246351],"category_scores_gemma":[0.0003834374,0.0002337627,0.00006438626,0.000215991,0.0004886844,0.0003861083,0.0001130019,0.000434437,1.494919e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005345332,"about_ca_system_score_gemma":0.0002848778,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005927039,"about_ca_topic_score_gemma":0.00001037305,"domain_scores_codex":[0.9983487,4.896707e-7,0.0007297532,0.0002831436,0.0003002397,0.0003376714],"domain_scores_gemma":[0.9977344,0.0008743725,0.0007688357,0.0003401873,0.0001625497,0.0001195987],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005302465,0.00005339661,0.02501669,0.0005978193,0.0001791153,0.00002588884,0.00149732,0.0004161328,0.971603,0.000003325657,0.000001079419,0.00007598311],"study_design_scores_gemma":[0.001897089,0.00003587765,0.002284313,0.0008729547,0.0003292123,0.002426177,0.003656067,0.0007230567,0.987421,0.00006569976,0.00002875194,0.0002598016],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950458,0.004048077,0.00007263759,0.000604197,0.00001504184,0.0001211209,0.0000563549,0.00002892394,0.00000778601],"genre_scores_gemma":[0.9981528,0.001422727,0.0000448069,0.00002464388,0.0001861826,0.000009474931,0.00005093727,0.00006994123,0.0000384731],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02273237,"threshold_uncertainty_score":0.9532567,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007431494348303681,"score_gpt":0.2307651402760973,"score_spread":0.2233336459277936,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}