{"id":"W2152695624","doi":"10.1186/1471-2148-10-374","title":"Conservation, loss, and redeployment of Wnt ligands in protostomes: implications for understanding the evolution of segment formation","year":2010,"lang":"en","type":"article","venue":"BMC Evolutionary Biology","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":189,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Los Alamos National Laboratory; Lawrence Berkeley National Laboratory; Lawrence Livermore National Laboratory; Biological and Environmental Research; National Cancer Institute; Office of Science; Centre National de la Recherche Scientifique; Agence Nationale de la Recherche; Eunice Kennedy Shriver National Institute of Child Health and Human Development; U.S. Department of Energy; European Commission; Joint Genome Institute; Lilly Endowment; National Institutes of Health; Terry Fox Foundation; Deutsche Forschungsgemeinschaft; Eli Lilly and Company; National Science Foundation","keywords":"Biology; Wnt signaling pathway; Evolutionary biology; Genetics; Gene; Annelid; Zoology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003204226,0.00007597463,0.00009958797,0.00006885201,0.00008840083,0.000001655505,0.00007786469,0.0001556682,0.000002074075],"category_scores_gemma":[0.00007940115,0.00005989562,0.00003388081,0.00009567611,0.0002627882,0.000008003347,0.00004890335,0.0000434304,2.208592e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005909477,"about_ca_system_score_gemma":0.0001398447,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002123396,"about_ca_topic_score_gemma":0.0003035894,"domain_scores_codex":[0.999355,0.00004014343,0.0003018618,0.0001631992,0.00002978155,0.0001100705],"domain_scores_gemma":[0.9995323,0.00005510159,0.000169174,0.000136086,0.00009031775,0.00001704416],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001150319,0.00003749845,0.3487394,0.00003105322,0.00001304891,7.081008e-9,0.0000432952,0.00002383738,0.608489,0.04221389,0.0001361741,0.0001576861],"study_design_scores_gemma":[0.0009005284,0.0003334218,0.8745217,0.00001842859,0.00001379701,0.00002565544,0.000350081,0.0004312619,0.07836293,0.04402169,0.0009018944,0.0001185669],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9321841,0.0004062371,0.06545514,0.0008907228,0.00008847847,0.0008610041,0.00005085507,0.00000467467,0.00005878409],"genre_scores_gemma":[0.9971722,0.00004437155,0.002101084,0.00003271124,0.00003145927,0.0002277095,0.0003606785,0.000004371082,0.00002535187],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5301262,"threshold_uncertainty_score":0.2442473,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02247016794489827,"score_gpt":0.2749408588409123,"score_spread":0.2524706908960141,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}