{"id":"W2152723838","doi":"10.1261/rna.1790509","title":"A systematic characterization of Cwc21, the yeast ortholog of the human spliceosomal protein SRm300","year":2009,"lang":"en","type":"article","venue":"RNA","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; National Institute of General Medical Sciences; Nederlandse Organisatie voor Wetenschappelijk Onderzoek","keywords":"Spliceosome; Biology; RNA splicing; Splicing factor; Exonic splicing enhancer; Genetics; Alternative splicing; Proteome; Zinc finger; Protein splicing; Computational biology; SR protein; RNA-binding protein; Cell biology; Gene; RNA; Gene isoform; Transcription factor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001811658,0.00005473633,0.0001039209,0.00001365598,0.00005780968,0.000006508768,0.0002010532,0.00004394465,0.000004351836],"category_scores_gemma":[0.0000594382,0.00002953146,0.0000794048,0.00006998792,0.00005107252,0.000001971308,0.00004203093,0.00005003754,0.000001380665],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003538701,"about_ca_system_score_gemma":0.00002456999,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009355228,"about_ca_topic_score_gemma":0.000005457687,"domain_scores_codex":[0.999414,0.00008819019,0.0001800925,0.00008840803,0.0001268536,0.0001024916],"domain_scores_gemma":[0.9994806,0.000002842414,0.0001230879,0.0003196594,0.00005535624,0.0000184321],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00000977762,0.00002580522,0.0004368493,0.0003583595,0.00001538823,3.639611e-7,0.00002849479,0.000001092716,0.9986645,0.0003309253,0.000009794318,0.0001186732],"study_design_scores_gemma":[0.0001262874,0.0001536155,0.04100339,0.0004068494,0.00001187167,0.000004891429,0.00002759999,0.00004697789,0.9580947,0.00004125744,0.0000384316,0.00004408507],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988275,0.00007142036,0.0000844786,0.0001533687,0.00001239994,0.0004592266,0.000006772259,0.000003223409,0.0003816442],"genre_scores_gemma":[0.9986877,0.000005963422,0.00001571607,0.00004771487,0.00004380114,0.00001510837,0.000009942732,0.000004488924,0.001169605],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04056973,"threshold_uncertainty_score":0.1204258,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008141372839897758,"score_gpt":0.2487026226621485,"score_spread":0.2405612498222507,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}