{"id":"W2152723932","doi":"10.1158/1078-0432.ccr-10-2273","title":"Biomarkers for Cetuximab-Based Neoadjuvant Radiochemotherapy in Locally Advanced Rectal Cancer","year":2011,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Colorectal Cancer Surgical Treatments","field":"Medicine","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"Response Biomedical (Canada)","funders":"","keywords":"KRAS; Cetuximab; Medicine; Colorectal cancer; Oncology; Internal medicine; Cancer; Cancer research; Epidermal growth factor receptor; Neoadjuvant therapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004149402,0.0003025055,0.0003554757,0.0007034293,0.0001932743,0.0004209827,0.0002069972,0.0003499434,0.001600937],"category_scores_gemma":[0.001197837,0.0001361472,0.0001661028,0.0004509285,0.0002061446,0.0001795668,0.0001991094,0.0003469063,0.0003125726],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003293275,"about_ca_system_score_gemma":0.0002636218,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004603638,"about_ca_topic_score_gemma":0.0008849844,"domain_scores_codex":[0.9998521,0.00004899692,0.00001601103,0.00002317733,0.00003931438,0.00002047828],"domain_scores_gemma":[0.9995204,0.0001114933,0.0002059836,0.00001703077,0.00006674839,0.00007836462],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003682317,0.0003500835,0.9088157,0.0002971976,0.0001545601,0.0002045564,0.00007557835,0.0009642655,0.0436138,0.00008139844,0.001053096,0.04070746],"study_design_scores_gemma":[0.0001768446,0.002187849,0.9745681,0.000060456,0.0001903651,0.001369622,0.0001377283,0.003930688,0.01402706,0.0001683747,0.00316906,0.00001379524],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944726,0.003647206,0.0006278357,0.000151473,0.00002517741,0.00006909167,0.000271313,0.00003640893,0.0006988584],"genre_scores_gemma":[0.9974317,0.0003685274,0.0009923166,0.00007072659,0.00001739713,0.00007007969,0.0005788245,0.000003017263,0.0004674674],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001600937,"threshold_uncertainty_score":0.005355716,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3959506586468158,"score_gpt":0.560738633194411,"score_spread":0.1647879745475952,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}