{"id":"W2152741235","doi":"10.1139/g08-023","title":"Mutations of the<i>withered</i>(<i>whd</i>) gene in<i>Drosophila melanogaster</i>confer hypersensitivity to oxidative stress and are lesions of the carnitine palmitoyltransferase I (CPT I) gene","year":2008,"lang":"en","type":"article","venue":"Genome","topic":"Peroxisome Proliferator-Activated Receptors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph; York University; Nipissing University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Genetics; Drosophila melanogaster; Gene; Mutant; Heteroplasmy; Mitochondrion; Allele; Oxidative stress; Phenotype; Paraquat; Mutation; Carnitine; Cell biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009142025,0.0002004915,0.0002646479,0.00005946363,0.0001519227,0.0000058807,0.0002277118,0.0001319288,0.000008814168],"category_scores_gemma":[0.00007063636,0.0001422976,0.0001070619,0.0002729255,0.0003123593,0.000007022933,0.00017312,0.0001554953,0.00000150244],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002233614,"about_ca_system_score_gemma":0.0001377335,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008059765,"about_ca_topic_score_gemma":0.0002212844,"domain_scores_codex":[0.9987661,0.0001943105,0.0002888233,0.0003342647,0.0001797133,0.0002368077],"domain_scores_gemma":[0.9991269,0.00002494725,0.0001335554,0.0004647448,0.0001574867,0.00009235369],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005713374,0.0001051654,0.02993657,0.00001896617,0.00005974938,0.000004816413,0.0008106701,0.0005696386,0.9683647,0.000005883529,0.000004677187,0.0000620217],"study_design_scores_gemma":[0.0004935648,0.00008399237,0.1357715,0.00003076631,0.00002291702,0.00004268129,0.0002797458,0.000003314152,0.8629463,0.00001360004,0.0001756737,0.0001359277],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977816,0.0003209448,0.0001096296,0.0003443545,0.00009202574,0.0004456189,0.0007795499,0.000005623132,0.0001206148],"genre_scores_gemma":[0.9991579,0.0001476722,0.0002411751,0.0002041815,0.00007562515,0.00002902444,0.00004333155,0.0000234773,0.00007761041],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1058349,"threshold_uncertainty_score":0.5802727,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01284915849871882,"score_gpt":0.2146410415319412,"score_spread":0.2017918830332224,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}