{"id":"W2152741235","doi":"10.1139/g08-023","title":"Mutations of the<i>withered</i>(<i>whd</i>) gene in<i>Drosophila melanogaster</i>confer hypersensitivity to oxidative stress and are lesions of the carnitine palmitoyltransferase I (CPT I) gene","year":2008,"lang":"en","type":"article","venue":"Genome","topic":"Peroxisome Proliferator-Activated Receptors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph; York University; Nipissing University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Genetics; Drosophila melanogaster; Gene; Mutant; Heteroplasmy; Mitochondrion; Allele; Oxidative stress; Phenotype; Paraquat; Mutation; Carnitine; Cell biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001119173,0.0007956158,0.0002146314,0.0006149577,0.0003683401,0.0002749413,0.0004540605,0.0004367605,0.00248408],"category_scores_gemma":[0.0001186366,0.0002666352,0.0004396111,0.0003031179,0.0005026339,0.0001565384,0.0003934662,0.0006976534,0.0007726663],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006283484,"about_ca_system_score_gemma":0.0002431742,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001432133,"about_ca_topic_score_gemma":0.004432126,"domain_scores_codex":[0.999815,0.00002467607,0.00002224606,0.00006336401,0.00004841617,0.0000262574],"domain_scores_gemma":[0.9997606,0.00004634417,0.0001159941,0.00002436137,0.00001459336,0.00003821668],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004081235,0.00001474276,0.0002511715,0.00002545512,0.000007991825,0.0001522898,0.000009957223,0.00004334603,0.9983227,0.00009655508,0.00006686421,0.0009681995],"study_design_scores_gemma":[0.00003667126,0.000192595,0.01857421,0.0000155941,0.00005036349,0.001536868,0.00006717601,0.0006885609,0.9705587,0.00007135161,0.008181931,0.00002597833],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9795169,0.0008113516,0.01032104,0.0002226831,0.0000932441,0.0001451543,0.0036434,0.0004644121,0.004781714],"genre_scores_gemma":[0.9708438,0.0008881544,0.01258552,0.0002357442,0.00002878786,0.0001006284,0.004776577,0.0002669058,0.01027378],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00248408,"threshold_uncertainty_score":0.00831008,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01284915849871882,"score_gpt":0.2146410415319412,"score_spread":0.2017918830332224,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}