{"id":"W2152748843","doi":"10.1016/s1474-4422(14)70065-1","title":"Frontotemporal dementia and its subtypes: a genome-wide association study","year":2014,"lang":"en","type":"article","venue":"The Lancet Neurology","topic":"Amyotrophic Lateral Sclerosis Research","field":"Medicine","cited_by":402,"is_retracted":false,"has_abstract":false,"ca_institutions":"Occupational Cancer Research Centre; University of Toronto; University of British Columbia","funders":"Pacific Alzheimer Research Foundation; National Institute on Aging; Medical Research Council; National Institute of Neurological Disorders and Stroke; National Institute for Health and Care Research; U.S. Bureau of Land Management; Háskólinn í Reykjavík; National Health and Medical Research Council; Miyuki Giken; Novo Nordisk Fonden; National Institutes of Health; Fondazione Cariplo; Canadian Institutes of Health Research; Hersenstichting; Rothamsted Research; Wellcome Trust","keywords":"Frontotemporal dementia; Genome-wide association study; Association (psychology); Dementia; Psychology; Medicine; Genetics; Biology; Disease; Single-nucleotide polymorphism; Internal medicine; Gene; Genotype; Psychotherapist","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002007168,0.00101268,0.001305285,0.001553547,0.001526309,0.001735505,0.001207313,0.001789784,0.002306763],"category_scores_gemma":[0.002753484,0.0009535204,0.002166474,0.003660375,0.0007267219,0.000968558,0.001113358,0.001511573,0.0002993188],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005353706,"about_ca_system_score_gemma":0.0005085092,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01837578,"about_ca_topic_score_gemma":0.02487097,"domain_scores_codex":[0.9986291,0.0003690298,0.0001742681,0.0004754073,0.0001726386,0.0001796029],"domain_scores_gemma":[0.9984692,0.0004975486,0.0004293651,0.0002434869,0.0001613555,0.0001989929],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003602284,0.0002570402,0.9778203,0.0001147865,0.005940793,0.001402388,0.0006117577,0.0001784477,0.003308216,0.0002560769,0.0009037293,0.005604171],"study_design_scores_gemma":[0.000153175,0.0001291762,0.9957475,0.00002244896,0.002189364,0.0005854144,0.0002986164,0.0002035202,0.00008381915,0.0001898195,0.0003801236,0.00001705669],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961191,0.001980156,0.0002007914,0.0002232664,0.0000327433,0.00001101547,0.0007655415,0.00001118811,0.0006560644],"genre_scores_gemma":[0.9982131,0.0005116473,0.0002614611,0.00007686179,0.00004221905,0.0000124384,0.0005024555,0.000009164236,0.0003706353],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01837578,"threshold_uncertainty_score":0.03653765,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03542560285476928,"score_gpt":0.2932006996329686,"score_spread":0.2577750967781993,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}