{"id":"W2152840183","doi":"10.1093/neuonc/nop017","title":"A phase I trial of erlotinib in patients with nonprogressive glioblastoma multiforme postradiation therapy, and recurrent malignant gliomas and meningiomas","year":2009,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Institute for Cancer Research","funders":"National Center for Research Resources; National Cancer Institute","keywords":"Erlotinib; Medicine; Rash; Toxicity; Pharmacokinetics; Gastroenterology; Diarrhea; Pharmacology; Internal medicine; Chemotherapy; Phases of clinical research; Oncology; Cancer; Epidermal growth factor receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001186952,0.001251269,0.002057941,0.0004180648,0.0003374167,0.000656381,0.0007373334,0.001080521,0.00187321],"category_scores_gemma":[0.0008107724,0.0004461998,0.001182926,0.000424872,0.0006128334,0.0006639526,0.0002686329,0.002095837,0.000499321],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007430405,"about_ca_system_score_gemma":0.001245304,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008297655,"about_ca_topic_score_gemma":0.002930851,"domain_scores_codex":[0.9996821,0.0001441045,0.0000216309,0.00004816594,0.00002628347,0.00007760615],"domain_scores_gemma":[0.9994431,0.00007862438,0.0001361245,0.00003671966,0.00003554609,0.0002698295],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7898781,0.03982093,0.006687021,0.0009946155,0.00184928,0.0006410162,0.0003665522,0.00274094,0.02464931,0.0004539408,0.00493252,0.1269857],"study_design_scores_gemma":[0.6219435,0.3571107,0.01241454,0.00004136159,0.0005443459,0.0006298278,0.00007373268,0.001212335,0.002604156,0.0002847501,0.003114345,0.00002648177],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914287,0.003101491,0.0004156583,0.0004717983,0.0001196677,0.001847598,0.0004237114,0.0000820288,0.002109246],"genre_scores_gemma":[0.9899489,0.002222128,0.001147314,0.0008917274,0.0001355476,0.002250629,0.001328403,0.00001886484,0.002056486],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002057941,"threshold_uncertainty_score":0.006277263,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01769246670536518,"score_gpt":0.3037294282658909,"score_spread":0.2860369615605257,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}