{"id":"W2152897137","doi":"10.1242/jcs.069484","title":"14-3-3σ associates with cell surface aminopeptidase N in the regulation of matrix metalloproteinase-1","year":2010,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"14-3-3 protein interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Biology; Ectodomain; Cell biology; Stromal cell; Matrix metalloproteinase; Phosphorylation; Extracellular matrix; Transmembrane protein; Signal transduction; Cancer research; Receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001012458,0.0002910169,0.0001455855,0.0001355491,0.0002956506,0.0003326439,0.0001789853,0.0002426952,0.000636904],"category_scores_gemma":[0.0001313763,0.0001389115,0.000203491,0.0001328667,0.0002630369,0.0001598017,0.0002810147,0.000251085,0.0005209387],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006211261,"about_ca_system_score_gemma":0.0003393007,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001180982,"about_ca_topic_score_gemma":0.001669185,"domain_scores_codex":[0.9998895,0.00001587099,0.000005307939,0.00002349357,0.00003026096,0.00003545048],"domain_scores_gemma":[0.9999349,0.000007325058,0.00001891664,0.000006816313,0.000007594283,0.00002433533],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001154401,0.00001244046,0.0007041139,0.00001069264,0.00000291013,0.00009396502,0.00001009392,0.00005674692,0.9979087,0.0001707529,0.0000280625,0.0008861846],"study_design_scores_gemma":[0.00002528201,0.0001329951,0.03514564,0.00001325003,0.00001576998,0.0007490298,0.0000653743,0.002944827,0.9566718,0.0004682183,0.003760134,0.000007723354],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946989,0.001705959,0.002204155,0.00009294247,0.00001480004,0.000007005186,0.00005461249,0.00003756,0.001183966],"genre_scores_gemma":[0.9964914,0.0006286275,0.0008434232,0.0000399152,0.000004793158,0.000007074282,0.0001355766,0.000007653339,0.001841636],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001180982,"threshold_uncertainty_score":0.004506588,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004982281488669403,"score_gpt":0.2493375238816418,"score_spread":0.2443552423929724,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}