{"id":"W2152914611","doi":"10.1126/stke.3522006re9","title":"Systems Biology of AGC Kinases in Fungi","year":2006,"lang":"en","type":"review","venue":"Science s STKE","topic":"Fungal and yeast genetics research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"Iogen Corporation","funders":"","keywords":"Biology; Saccharomyces cerevisiae; Kinase; Mutant; Cell biology; Protein kinase A; Phenotype; Cell growth; Signal transduction; Computational biology; Genetics; Yeast; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005055488,0.00116674,0.001308319,0.001488827,0.0004240531,0.001395185,0.001200262,0.001390339,0.002791374],"category_scores_gemma":[0.0003319159,0.0004011065,0.0004100529,0.001529078,0.0009210724,0.001715011,0.0007017757,0.001202388,0.002954189],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001482434,"about_ca_system_score_gemma":0.001107506,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00121683,"about_ca_topic_score_gemma":0.001509989,"domain_scores_codex":[0.9998324,0.00002652346,0.00001746913,0.00003898944,0.00006790327,0.00001659384],"domain_scores_gemma":[0.9998629,0.00005217563,0.00001835685,0.00001163057,0.00003563417,0.0000193028],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005919414,0.00006790319,0.0001545363,0.01064511,0.00008338824,0.0005588588,0.0001610672,0.002923152,0.01337806,0.04690071,0.02349044,0.9015776],"study_design_scores_gemma":[0.0000140989,0.00006294055,0.000281006,0.0009333258,0.0000275628,0.001014457,0.00004547519,0.0003359065,0.001863675,0.01149021,0.9839135,0.00001775818],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002659895,0.9941674,0.00176871,0.0003076301,0.0002763462,0.0000103025,0.00001517471,0.00002476019,0.0031636],"genre_scores_gemma":[0.002785035,0.9927254,0.001773724,0.0002299573,0.0002565487,0.00002489918,0.00004421007,0.000003952621,0.002156326],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002791374,"threshold_uncertainty_score":0.01075584,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04841442932079096,"score_gpt":0.3883662887694706,"score_spread":0.3399518594486797,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}