{"id":"W2152983088","doi":"10.1002/btpr.286","title":"Reassessing culture media and critical metabolites that affect adenovirus production","year":2009,"lang":"en","type":"article","venue":"Biotechnology Progress","topic":"Viral Infectious Diseases and Gene Expression in Insects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"Biotechnology Research Institute","funders":"","keywords":"Cell culture; Nutrient; HEK 293 cells; Cell growth; Cell; Biology; Metabolism; Biochemistry; Ammonia production; Limiting; Ammonia; Chemistry; Food science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001098362,0.0001964585,0.0001720851,0.00008099993,0.0002048835,0.00005992796,0.000147271,0.0005493353,0.000007076206],"category_scores_gemma":[0.0003783443,0.0001610702,0.00006463843,0.0001333435,0.0004478403,0.00001325026,0.00007564171,0.0001784627,0.000004011286],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007971591,"about_ca_system_score_gemma":0.0000264042,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001923571,"about_ca_topic_score_gemma":0.000002659749,"domain_scores_codex":[0.9988568,0.00006446885,0.0001316871,0.0005300093,0.0001160908,0.0003009712],"domain_scores_gemma":[0.9994196,0.000009184883,0.00006265952,0.0003517072,0.00006311525,0.00009376356],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008712016,0.0001650832,0.005381714,0.00002863778,0.00003424812,0.00001281419,0.00003919399,6.34014e-7,0.9442197,0.002313665,0.003799598,0.04391758],"study_design_scores_gemma":[0.0002647546,0.0004709815,0.01120823,0.00004486211,0.00004952782,0.0001576969,0.00007275075,0.000006976859,0.9727966,0.002021753,0.01264628,0.0002595529],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9627532,0.03229854,0.0002289675,0.00369338,0.0004628976,0.0002243638,0.00001160292,0.0001743462,0.0001526811],"genre_scores_gemma":[0.9964241,0.001148267,0.001662466,0.0002474832,0.0003719402,0.00003039969,0.00003487753,0.00001475648,0.00006567971],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04365803,"threshold_uncertainty_score":0.656825,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0139402479705833,"score_gpt":0.3000879077496092,"score_spread":0.2861476597790259,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}