{"id":"W2152983088","doi":"10.1002/btpr.286","title":"Reassessing culture media and critical metabolites that affect adenovirus production","year":2009,"lang":"en","type":"article","venue":"Biotechnology Progress","topic":"Viral Infectious Diseases and Gene Expression in Insects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"Biotechnology Research Institute","funders":"","keywords":"Cell culture; Nutrient; HEK 293 cells; Cell growth; Cell; Biology; Metabolism; Biochemistry; Ammonia production; Limiting; Ammonia; Chemistry; Food science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00139257,0.0006716026,0.0006562671,0.0003451166,0.0003312411,0.001274514,0.0005416258,0.0005198003,0.000689042],"category_scores_gemma":[0.001698007,0.0002075654,0.0003809039,0.0004116222,0.0004158563,0.0008593492,0.0005198197,0.0008871775,0.0003468683],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006909819,"about_ca_system_score_gemma":0.0004748214,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001730397,"about_ca_topic_score_gemma":0.002699471,"domain_scores_codex":[0.9991592,0.0001997528,0.0001581956,0.0001456565,0.0002542554,0.00008285436],"domain_scores_gemma":[0.9988719,0.0005496017,0.0001873951,0.00006524922,0.0002743105,0.00005152225],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001802464,0.00007132246,0.001685047,0.0001892414,0.00001774117,0.0001438629,0.00009942929,0.0001746667,0.992866,0.0001022524,0.00008815981,0.00438191],"study_design_scores_gemma":[0.000004766563,0.0002997548,0.00338352,0.00003475136,0.00003683186,0.0001215937,0.00009797926,0.0006633869,0.9914766,0.00005425428,0.003812192,0.00001435702],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9619213,0.009630126,0.02158292,0.0006053217,0.0003314897,0.0004649788,0.00118456,0.0002958287,0.003983356],"genre_scores_gemma":[0.9181367,0.00729936,0.06477325,0.0008748659,0.0000856957,0.0007122612,0.00279617,0.0002799284,0.005041859],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001730397,"threshold_uncertainty_score":0.00736469,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0139402479705833,"score_gpt":0.3000879077496092,"score_spread":0.2861476597790259,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}