{"id":"W215298869","doi":"10.1007/s00232-001-0027-z","title":"The Composition-Dependent Presence of Free (Micellar) Alkylphospholipid in Liposomal Formulations of Octadecyl-1,1-dimethyl-piperidino-4-yl-phosphate Affects its Cytotoxic Activity in vitro","year":2001,"lang":"en","type":"article","venue":"The Journal of Membrane Biology","topic":"Lipid Membrane Structure and Behavior","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Liposome; Cytotoxicity; Chemistry; Cholesterol; Chromatography; Phosphate; Membrane; In vitro; Monolayer; Micelle; Biochemistry; Organic chemistry; Aqueous solution","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001618639,0.0002977849,0.0001962816,0.0001184453,0.00009453606,0.0002835528,0.0001820376,0.0002248484,0.0008255045],"category_scores_gemma":[0.0002400961,0.0001522196,0.0001171425,0.0001452812,0.0002278175,0.0003209185,0.0001659435,0.0004294557,0.0002517978],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001845257,"about_ca_system_score_gemma":0.0002433795,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004445666,"about_ca_topic_score_gemma":0.0004334358,"domain_scores_codex":[0.9999018,0.00002376017,0.00001426961,0.00001719,0.00002084348,0.00002216434],"domain_scores_gemma":[0.9998612,0.00004436755,0.00003186162,0.00001229814,0.00002194718,0.00002826762],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004692521,0.00002710919,0.00007788814,0.00003814334,0.000006339405,0.00003178536,0.00001471853,0.00006992749,0.9983293,0.00005945773,0.00001742925,0.0008585764],"study_design_scores_gemma":[0.00001480914,0.0001946821,0.0002930783,0.000003290906,0.00001880168,0.00004209593,0.000006446902,0.0001681515,0.9989173,0.00001150886,0.0003279608,0.000001968742],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968243,0.001341587,0.0008874282,0.00004400055,0.00003142377,0.00001457013,0.0001150989,0.00002494833,0.0007166703],"genre_scores_gemma":[0.9969471,0.001017472,0.0006994031,0.00002865894,0.00001051291,0.00001816783,0.0002311803,0.00001282595,0.001034766],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008255045,"threshold_uncertainty_score":0.002761543,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0113011339297233,"score_gpt":0.2634761176623526,"score_spread":0.2521749837326293,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}