{"id":"W2153018245","doi":"10.1093/chromsci/bmt106","title":"Simultaneous Measurement of N-Acetyl-S-(2-cyanoethyl)-cysteine and N-Acetyl-S-(2-hydroxyethyl)-cysteine in Human Urine by Liquid Chromatography-Tandem Mass Spectrometry","year":2013,"lang":"en","type":"article","venue":"Journal of Chromatographic Science","topic":"Sulfur Compounds in Biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Natural Science Foundation of China; Egg Farmers of Canada; National Science Foundation","keywords":"Chemistry; Chromatography; Detection limit; Tandem mass spectrometry; Mass spectrometry; Acrylonitrile; Urine; Electrospray ionization; Liquid chromatography–mass spectrometry; Cysteine; Organic chemistry; Biochemistry; Enzyme","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008526272,0.0006616962,0.0007180869,0.001415196,0.0004394398,0.0004175016,0.0005125873,0.001138995,0.0002866425],"category_scores_gemma":[0.001396082,0.000361753,0.000359026,0.0009015327,0.0004308254,0.000322685,0.0003891788,0.0004711275,0.0002255894],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003821048,"about_ca_system_score_gemma":0.000767681,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001980756,"about_ca_topic_score_gemma":0.00429086,"domain_scores_codex":[0.9985315,0.0003648201,0.00009102506,0.0003665194,0.0005783513,0.00006777593],"domain_scores_gemma":[0.9993975,0.0001280998,0.0001192847,0.0000364281,0.0002609966,0.00005769655],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003401657,0.0000749936,0.006430606,0.0001021485,0.0001017085,0.0001160205,0.00006964289,0.0001930426,0.9821448,0.0000419587,0.00008176667,0.01030308],"study_design_scores_gemma":[0.00004654144,0.0007278056,0.03006479,0.00001794813,0.0001333272,0.001394224,0.00006362703,0.005622609,0.9605941,0.00009759417,0.001192683,0.000044786],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.9614301,0.005795158,0.03046599,0.0001323461,0.00008036695,0.0001530889,0.0006590005,0.0004554696,0.0008285808],"genre_scores_gemma":[0.9302733,0.002621457,0.06366781,0.0003028119,0.0000530982,0.0002803569,0.0006943067,0.00004005483,0.002066848],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.001980756,"threshold_uncertainty_score":0.004509211,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008496951802532788,"score_gpt":0.2436977064444596,"score_spread":0.2352007546419268,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}