{"id":"W2153018245","doi":"10.1093/chromsci/bmt106","title":"Simultaneous Measurement of N-Acetyl-S-(2-cyanoethyl)-cysteine and N-Acetyl-S-(2-hydroxyethyl)-cysteine in Human Urine by Liquid Chromatography-Tandem Mass Spectrometry","year":2013,"lang":"en","type":"article","venue":"Journal of Chromatographic Science","topic":"Sulfur Compounds in Biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Natural Science Foundation of China; Egg Farmers of Canada; National Science Foundation","keywords":"Chemistry; Chromatography; Detection limit; Tandem mass spectrometry; Mass spectrometry; Acrylonitrile; Urine; Electrospray ionization; Liquid chromatography–mass spectrometry; Cysteine; Organic chemistry; Biochemistry; Enzyme","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002443737,0.0004258617,0.0008031975,0.001180905,0.0001844113,0.00008194555,0.001137527,0.0002734459,0.00003856443],"category_scores_gemma":[0.0005191658,0.0003698595,0.0002607444,0.001956787,0.001899828,0.00006535613,0.0002741109,0.000376114,0.000001920222],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008476393,"about_ca_system_score_gemma":0.000256519,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008233937,"about_ca_topic_score_gemma":0.00003532827,"domain_scores_codex":[0.9958311,0.0001990205,0.001360227,0.000660515,0.001200967,0.0007481925],"domain_scores_gemma":[0.9969563,0.00008470935,0.001034184,0.0006570932,0.0009016857,0.0003660206],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000908124,0.0002186662,0.01638776,0.00005976498,0.0001046984,0.00002447868,0.00005480163,0.00005142945,0.9825673,0.00004521053,0.0002635158,0.0001316164],"study_design_scores_gemma":[0.002691448,0.009206016,0.005621545,0.0002420087,0.00004568183,0.0008009678,0.0002231833,0.0001526472,0.9792802,0.0003284743,0.0009127244,0.0004950567],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9909171,0.00708781,0.000710466,0.0002456305,0.0002950524,0.0003752138,0.000007140701,0.00001615082,0.0003454173],"genre_scores_gemma":[0.99567,0.0009760316,0.003019378,0.0001000281,0.0001582631,0.00001482825,0.000005593772,0.00003599797,0.00001987287],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01076622,"threshold_uncertainty_score":0.9998753,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008496951802532788,"score_gpt":0.2436977064444596,"score_spread":0.2352007546419268,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}