{"id":"W2153089127","doi":"10.1093/carcin/bgp300","title":"Hypomethylation and genome instability in the germline of exposed parents and their progeny is associated with altered miRNA expression","year":2009,"lang":"en","type":"article","venue":"Carcinogenesis","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":110,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Lethbridge","funders":"","keywords":"Biology; Germline; DNA methylation; Epigenetics; Genome instability; Methylation; Genetics; Somatic cell; Epigenome; microRNA; DNA damage; DNA; Gene expression; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001269479,0.0001916318,0.0001836882,0.0002778762,0.0001535262,0.0002089889,0.0001356305,0.0002135275,0.001343574],"category_scores_gemma":[0.0001556153,0.000123076,0.0001619837,0.0001086402,0.0001553732,0.0001071851,0.0002253184,0.000354895,0.0002159947],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000130502,"about_ca_system_score_gemma":0.0001230294,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002896004,"about_ca_topic_score_gemma":0.0004699483,"domain_scores_codex":[0.9998634,0.00002093127,0.000009414921,0.00005331988,0.0000379405,0.00001502312],"domain_scores_gemma":[0.9998305,0.00002177482,0.00008209655,0.00001895036,0.00001832631,0.00002827298],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003331089,0.000005045343,0.001964357,0.00001146162,0.00000891707,0.00007517356,0.00002447436,0.000008087847,0.9968839,0.00004299783,0.000007270603,0.0009349998],"study_design_scores_gemma":[0.00000556229,0.0003423981,0.1838555,0.00000860894,0.0000707329,0.002018492,0.0001217791,0.0004896606,0.8102326,0.0001495741,0.002696266,0.000008840808],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938864,0.001406483,0.003720133,0.00003381899,0.00000987448,0.00000859933,0.0002007552,0.00005595224,0.000678024],"genre_scores_gemma":[0.9967123,0.0005055146,0.001106298,0.00001814793,0.000003896752,0.00001054631,0.0002647279,0.00001432524,0.001364169],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001343574,"threshold_uncertainty_score":0.004494727,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01974873244406047,"score_gpt":0.2393525549674473,"score_spread":0.2196038225233868,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}