{"id":"W2153105150","doi":"10.1093/nar/gks022","title":"A human XRCC4–XLF complex bridges DNA","year":2012,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":160,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Brookhaven National Laboratory; National Cancer Institute; Canadian Institutes of Health Research; National Institute of Biomedical Imaging and Bioengineering; McMaster University","keywords":"DNA repair protein XRCC4; DNA ligase; Biology; Non-homologous end joining; DNA repair; DNA; Genetics; Ubiquitin ligase; Cell biology; Nucleotide excision repair; Ubiquitin; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001299796,0.0001594389,0.0001545773,0.0001127811,0.0003098916,0.00005899188,0.0005289901,0.0002133209,0.0005904525],"category_scores_gemma":[0.0001683134,0.0001544945,0.00010261,0.0001853365,0.0002418202,0.00000965479,0.0005826685,0.0002858894,0.000571855],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005089762,"about_ca_system_score_gemma":0.000055157,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004727655,"about_ca_topic_score_gemma":0.00001360227,"domain_scores_codex":[0.9976425,0.0002698993,0.0001889133,0.0003798305,0.0005782855,0.0009405971],"domain_scores_gemma":[0.9987184,0.00001766366,0.00003404974,0.0007416639,0.0001865441,0.0003017273],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002644919,0.0001411747,0.003336529,0.0000182346,0.00003133729,0.000003711588,0.00009510706,6.449165e-7,0.9625192,0.002308009,0.02949456,0.002025104],"study_design_scores_gemma":[0.0005746038,0.0005598259,0.03712286,0.00001419882,0.000007993063,0.0000359362,0.0003431257,0.00005881085,0.6609528,0.0003425694,0.2996861,0.0003011333],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.973343,0.0002896009,0.0001363919,0.0002429696,0.0001096147,0.0002657235,0.00001581681,0.00004677118,0.02555015],"genre_scores_gemma":[0.9916696,0.00002695171,0.0009315045,0.0001772629,0.0007461043,0.00004125448,0.00008478855,0.0000568746,0.006265691],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3015663,"threshold_uncertainty_score":0.735023,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07946739996205043,"score_gpt":0.374799931609877,"score_spread":0.2953325316478265,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}