{"id":"W2153105150","doi":"10.1093/nar/gks022","title":"A human XRCC4–XLF complex bridges DNA","year":2012,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":160,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Brookhaven National Laboratory; National Cancer Institute; Canadian Institutes of Health Research; National Institute of Biomedical Imaging and Bioengineering; McMaster University","keywords":"DNA repair protein XRCC4; DNA ligase; Biology; Non-homologous end joining; DNA repair; DNA; Genetics; Ubiquitin ligase; Cell biology; Nucleotide excision repair; Ubiquitin; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002072275,0.0004367793,0.0001973763,0.0003162656,0.0003460503,0.0003100073,0.0003316948,0.0005058901,0.003564107],"category_scores_gemma":[0.0002558935,0.0002203148,0.0002580344,0.0002568156,0.0002169822,0.0002275188,0.0001778681,0.0002603338,0.001041394],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007189452,"about_ca_system_score_gemma":0.0002529426,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001045214,"about_ca_topic_score_gemma":0.0009133131,"domain_scores_codex":[0.9998555,0.00001591765,0.000007864905,0.00005673089,0.00004239868,0.00002152703],"domain_scores_gemma":[0.9999131,0.00001212371,0.00002378574,0.00001234306,0.00001064868,0.00002800261],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003508969,0.00005958591,0.002333669,0.0001638137,0.00005785535,0.000379404,0.00002302826,0.0003783109,0.9843453,0.0004862146,0.0009637672,0.01045822],"study_design_scores_gemma":[0.0001149973,0.0004977633,0.02642497,0.0000175128,0.00005925497,0.001749015,0.00003326528,0.002618362,0.9352519,0.0003099573,0.0329056,0.0000175825],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9766003,0.00669497,0.01079563,0.0004793376,0.0001311312,0.0001022669,0.001684577,0.0005599375,0.002951827],"genre_scores_gemma":[0.9809765,0.001236851,0.006720672,0.00006871982,0.00002562646,0.00002813178,0.0045893,0.0000242085,0.006329952],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003564107,"threshold_uncertainty_score":0.01192319,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07946739996205043,"score_gpt":0.374799931609877,"score_spread":0.2953325316478265,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}