{"id":"W2153128301","doi":"10.1002/cbic.201200598","title":"Nonribosomal Assembly of Natural Lipocyclocarbamate Lipoprotein‐Associated Phospholipase Inhibitors","year":2013,"lang":"en","type":"article","venue":"ChemBioChem","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research; McMaster University","keywords":"Nonribosomal peptide; Chemistry; Lipoprotein; Biochemistry; Computational biology; Stereochemistry; Biology; Enzyme; Biosynthesis; Cholesterol","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001725232,0.0002792679,0.0001771575,0.0001282891,0.0001358902,0.0004680581,0.000195745,0.0003179847,0.001614987],"category_scores_gemma":[0.0002985283,0.000129521,0.0001958993,0.0001015462,0.0001745473,0.0002935796,0.0002901772,0.000408838,0.0009017869],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003474044,"about_ca_system_score_gemma":0.0002212151,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000171709,"about_ca_topic_score_gemma":0.0002884043,"domain_scores_codex":[0.9998503,0.00003496907,0.00001063081,0.000035683,0.00003990087,0.00002853929],"domain_scores_gemma":[0.9998965,0.00002373431,0.00002873956,0.00001594184,0.00001115023,0.00002382812],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001174792,0.00004606996,0.0000876275,0.00009325879,0.000008702393,0.0001090549,0.00003738894,0.0005224467,0.9911324,0.001244726,0.0002364242,0.006364391],"study_design_scores_gemma":[0.00001741515,0.0002296411,0.0002169033,0.000007949412,0.000008438718,0.00008375089,0.00001314958,0.001443472,0.9894438,0.0001382774,0.008390683,0.000006456931],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9441262,0.009699739,0.02958734,0.0005364056,0.000315067,0.0002037446,0.0003181782,0.0005041444,0.01470925],"genre_scores_gemma":[0.9778638,0.002335357,0.01266906,0.0001529221,0.00004869725,0.0000707787,0.0003190823,0.00006749733,0.006472722],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001614987,"threshold_uncertainty_score":0.005402684,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006882714233158006,"score_gpt":0.2150201763651106,"score_spread":0.2081374621319526,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}