{"id":"W2153128301","doi":"10.1002/cbic.201200598","title":"Nonribosomal Assembly of Natural Lipocyclocarbamate Lipoprotein‐Associated Phospholipase Inhibitors","year":2013,"lang":"en","type":"article","venue":"ChemBioChem","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research; McMaster University","keywords":"Nonribosomal peptide; Chemistry; Lipoprotein; Biochemistry; Computational biology; Stereochemistry; Biology; Enzyme; Biosynthesis; Cholesterol","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001645912,0.0002794014,0.000514914,0.00008720363,0.00006136249,0.00003111978,0.0001608906,0.0002563209,0.0004190192],"category_scores_gemma":[0.0005549191,0.0002147538,0.0002336498,0.000389172,0.0001347655,0.0001313362,0.000102157,0.0003473561,0.0001651176],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009509891,"about_ca_system_score_gemma":0.00007805316,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005274863,"about_ca_topic_score_gemma":0.00000656694,"domain_scores_codex":[0.9983693,0.00002416113,0.0004520378,0.0004107538,0.0003163129,0.0004273816],"domain_scores_gemma":[0.9987168,0.00004011367,0.0002310413,0.0004221641,0.0004048809,0.0001849825],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007341837,0.0002455359,0.0002936584,0.0001443165,0.0001143244,0.000009966928,0.00007564484,8.466328e-8,0.9807382,0.0000171606,0.01255643,0.005731317],"study_design_scores_gemma":[0.0009663008,0.0001255431,0.004919186,0.0002425719,0.0000894354,0.00002744178,0.00006110469,0.00004932705,0.9924529,0.00002349024,0.0007933138,0.0002493481],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936234,0.001272761,5.843056e-7,0.001968603,0.0003428425,0.0006705183,0.00001282362,0.0001119447,0.001996554],"genre_scores_gemma":[0.9954389,0.00004094179,0.0003752995,0.0003967942,0.0003419844,0.00000739178,0.00006985909,0.00003899582,0.003289818],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01176311,"threshold_uncertainty_score":0.8757406,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006882714233158006,"score_gpt":0.2150201763651106,"score_spread":0.2081374621319526,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}