{"id":"W2153134282","doi":"10.1093/infdis/jit807","title":"Toll-like Receptor Polymorphism Associations With HIV-1 Outcomes Among Sub-Saharan Africans","year":2013,"lang":"en","type":"article","venue":"The Journal of Infectious Diseases","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Allergy and Infectious Diseases; National Cancer Institute; National Human Genome Research Institute; National Institute of Mental Health; National Heart, Lung, and Blood Institute; Center for AIDS Research, University of Washington; National Institute on Drug Abuse; U.S. Public Health Service; National Institutes of Health; University of Cape Town; National Institute on Aging; University of Washington; Harvard University; Bill and Melinda Gates Foundation","keywords":"Single-nucleotide polymorphism; Haplotype; Immunology; Odds ratio; TLR9; Toll-like receptor; Medicine; TLR2; Biology; Genotype; Internal medicine; Genetics; Immune system; Gene; TLR4; Innate immune system; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003815166,0.0002400583,0.0001867402,0.0004042303,0.0003086801,0.0002739964,0.0001468936,0.0002176949,0.00223372],"category_scores_gemma":[0.001536987,0.000139128,0.0001492122,0.0004584663,0.0002163365,0.0001687126,0.0002507578,0.000255175,0.0001015686],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000904605,"about_ca_system_score_gemma":0.0001119574,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001211627,"about_ca_topic_score_gemma":0.001188795,"domain_scores_codex":[0.9998108,0.00007714223,0.00001604551,0.00003359316,0.00002625286,0.00003627517],"domain_scores_gemma":[0.9995371,0.000116322,0.0002235666,0.00002518825,0.00003009592,0.00006767612],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002208425,0.00002382646,0.9970962,0.00001105966,0.00006038184,0.0001001663,0.0001083458,0.00004927273,0.0008575526,0.00003069279,0.00003622853,0.001405316],"study_design_scores_gemma":[0.00001464986,0.0001389756,0.9985306,0.00001139107,0.00005422282,0.0004280462,0.0001631718,0.000168185,0.0002786238,0.00006260657,0.0001468913,0.00000263224],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9996461,0.0001522379,0.00002817529,0.00001824629,0.000001216347,0.000001533344,0.000062972,7.168791e-7,0.00008881771],"genre_scores_gemma":[0.9998535,0.00004151553,0.00002720851,0.000005230465,0.000002255137,0.000001447251,0.0000250109,3.381797e-7,0.00004354501],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00223372,"threshold_uncertainty_score":0.007472515,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004998044426828259,"score_gpt":0.2005789770744644,"score_spread":0.1955809326476362,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}