{"id":"W2153134843","doi":"10.1097/01.anes.0000296068.80921.10","title":"Mechanical Ventilation with Lower Tidal Volumes and Positive End-expiratory Pressure Prevents Pulmonary Inflammation in Patients without Preexisting Lung Injury","year":2008,"lang":"en","type":"article","venue":"Anesthesiology","topic":"Respiratory Support and Mechanisms","field":"Medicine","cited_by":272,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Medicine; Bronchoalveolar lavage; Mechanical ventilation; Ventilation (architecture); Tidal volume; Positive end-expiratory pressure; Lung; Anesthesia; Internal medicine; Respiratory system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002633289,0.0002912814,0.0006655929,0.0001123612,0.0002568668,0.0002268874,0.0002224448,0.0003057754,0.000955355],"category_scores_gemma":[0.000990523,0.00008590501,0.0002208802,0.0001019287,0.0003650131,0.0001999147,0.0002278056,0.0003828366,0.0001473046],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001414695,"about_ca_system_score_gemma":0.0002836477,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001299175,"about_ca_topic_score_gemma":0.0002816452,"domain_scores_codex":[0.999863,0.00004203323,0.00001657609,0.00002065397,0.00001857554,0.00003905279],"domain_scores_gemma":[0.9996296,0.0000806924,0.00009807885,0.00002088391,0.00001652617,0.0001541094],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.2048537,0.01683442,0.2718838,0.001161676,0.0006663903,0.00187294,0.0004602351,0.001384179,0.2491013,0.000298087,0.002011292,0.249472],"study_design_scores_gemma":[0.01410168,0.2437257,0.7200654,0.000165959,0.0004143998,0.003030661,0.0003232288,0.001391845,0.0131636,0.0002587504,0.003321009,0.00003770654],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990743,0.0005004803,0.0001282044,0.00006008464,0.00001783839,0.00002603265,0.00001519804,0.000005021483,0.0001727734],"genre_scores_gemma":[0.9991542,0.0002110576,0.0002757595,0.00008711477,0.00004518386,0.00005641092,0.00009111466,9.288516e-7,0.00007826177],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000955355,"threshold_uncertainty_score":0.003195941,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009690927057425205,"score_gpt":0.2387800038606069,"score_spread":0.2290890768031817,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}