{"id":"W2153168747","doi":"10.1073/pnas.1109540109","title":"Forkhead box transcription factor FoxC1 preserves corneal transparency by regulating vascular growth","year":2011,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Corneal surgery and disorders","field":"Medicine","cited_by":100,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Eye Institute; National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health; Ministero della Salute; Northwestern University","keywords":"Biology; Vascular endothelial growth factor; Transcription factor; Angiogenesis; Cornea; Matrix metalloproteinase; Vascular endothelial growth factor C; Vascular remodelling in the embryo; Cell biology; Extracellular matrix; Vascular endothelial growth factor A; Cancer research; Endocrinology; Genetics; VEGF receptors; Neuroscience","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006773673,0.0001069675,0.0002012437,0.0001096184,0.0001571881,0.000009576696,0.0003329918,0.00009272893,0.00008505775],"category_scores_gemma":[0.0002750563,0.00007236809,0.0001734023,0.0005457942,0.0004997816,0.0005186043,0.00002289302,0.0001455406,7.134624e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001936934,"about_ca_system_score_gemma":0.00003243466,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004034043,"about_ca_topic_score_gemma":2.197733e-7,"domain_scores_codex":[0.9982129,0.000007011665,0.000373593,0.0002390178,0.0009880683,0.0001793875],"domain_scores_gemma":[0.9993967,0.00005649204,0.0002477339,0.000009163765,0.0002297088,0.00006017694],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002289139,0.0003407378,0.2141394,0.0005333489,0.00007471762,1.438055e-8,0.00238802,0.00000421687,0.7457862,0.03250272,0.001458432,0.002543305],"study_design_scores_gemma":[0.0005072668,0.0001671863,0.5230758,0.0002076308,0.00005361594,0.000005587743,0.0003209544,0.0003648995,0.4316694,0.04332782,0.0001805638,0.000119243],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9842544,0.0003252214,0.00001451767,0.001410231,0.0000215299,0.0002705123,0.00001769871,0.00002191284,0.01366394],"genre_scores_gemma":[0.9988766,0.00004801437,0.0007378254,0.0001821826,0.00003322523,0.00001141767,6.207503e-7,0.000005276945,0.0001048611],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3141167,"threshold_uncertainty_score":0.2951085,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08561253945199919,"score_gpt":0.2904416895537671,"score_spread":0.2048291501017679,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}