{"id":"W2153168932","doi":"10.1111/j.1399-0004.2012.01900.x","title":"Recommendations for the predictive genetic test in Huntington's disease","year":2012,"lang":"en","type":"article","venue":"Clinical Genetics","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":232,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Predictive testing; Huntington's disease; Test (biology); Genetic testing; Disease; Genetics; Medicine; Biology; Internal medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.03296764,0.001480971,0.002114834,0.006466255,0.002002575,0.003749608,0.007614209,0.0198675,0.006665202],"category_scores_gemma":[0.1148252,0.001264695,0.004608332,0.003840123,0.003476487,0.004849868,0.002943253,0.02335955,0.007320193],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004383206,"about_ca_system_score_gemma":0.01728086,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01963645,"about_ca_topic_score_gemma":0.02052292,"domain_scores_codex":[0.9650703,0.01499957,0.009057941,0.001075684,0.0086392,0.001157303],"domain_scores_gemma":[0.872488,0.05370375,0.00696344,0.002211045,0.05961462,0.005019078],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008897742,0.0001968963,0.0009899321,0.002301034,0.0000574224,0.0007486026,0.0006733072,0.0005987204,0.0003478889,0.008579608,0.8324847,0.1529329],"study_design_scores_gemma":[0.0002315916,0.0001419706,0.00307782,0.02835844,0.0002899781,0.001748081,0.0007224099,0.0009247865,0.0003629493,0.01983843,0.9441671,0.0001365093],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"methods","genre_scores_codex":[0.001402851,0.08777277,0.02436058,0.8127993,0.03795686,0.001749514,0.001505701,0.0007832422,0.03166906],"genre_scores_gemma":[0.01578058,0.147398,0.257441,0.5008833,0.02733348,0.007326369,0.007345577,0.0005267849,0.03596487],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.03296764,"threshold_uncertainty_score":0,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1464959287774463,"score_gpt":0.4006660556446233,"score_spread":0.254170126867177,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}