{"id":"W2153224292","doi":"10.1097/ftd.0b013e318167909a","title":"First Clinical Experience With the New Once-Daily Formulation of Tacrolimus","year":2008,"lang":"en","type":"review","venue":"Therapeutic Drug Monitoring","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Astellas Pharma","keywords":"Tacrolimus; Medicine; Dosing; Trough level; Liver transplantation; Regimen; Calcineurin; Kidney transplantation; Kidney transplant; Intensive care medicine; Internal medicine; Transplantation","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001013541,0.0003183738,0.001132319,0.00006801406,0.0001237031,0.0000152784,0.0001828955,0.000123816,0.0000133816],"category_scores_gemma":[0.000005905681,0.0001592326,0.0004145628,0.0002400266,0.00008246507,0.00007215712,0.00001517899,0.0003013317,0.00001604715],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007274473,"about_ca_system_score_gemma":0.0002533343,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008077674,"about_ca_topic_score_gemma":0.000004440776,"domain_scores_codex":[0.9983857,0.00007405467,0.0006505663,0.0002740995,0.0003956801,0.0002198483],"domain_scores_gemma":[0.9985193,0.0004684225,0.0004045557,0.0004395114,0.00005421356,0.0001139819],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001301813,0.0001065769,0.01358827,0.002938639,0.0008561137,0.00005163334,0.002170813,0.00001002267,3.222317e-7,0.00003059439,0.00001180037,0.980105],"study_design_scores_gemma":[0.003527178,0.0004821298,0.02215613,0.04061261,0.003649577,0.0005408669,0.0003276822,0.00001430142,0.0000570504,0.0000154102,0.9281471,0.000469907],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001489602,0.9965561,0.0002514142,0.00008394643,0.000403698,0.0008314163,0.000005794192,0.0000407173,0.0003372988],"genre_scores_gemma":[0.03238821,0.9654637,0.0003856813,0.00002313588,0.0005212612,0.00004956566,0.00001674559,0.00004778081,0.001103931],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9796351,"threshold_uncertainty_score":0.6493317,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1283552152306986,"score_gpt":0.4239404030379041,"score_spread":0.2955851878072054,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}