{"id":"W2153237652","doi":"10.1002/hep.27913","title":"Interferon‐inducible cholesterol‐25‐hydroxylase restricts hepatitis C virus replication through blockage of membranous web formation","year":2015,"lang":"en","type":"article","venue":"Hepatology","topic":"Cholesterol and Lipid Metabolism","field":"Medicine","cited_by":85,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Helmholtz-Gemeinschaft","keywords":"Virology; Hepatitis C virus; Biology; Interferon; Viral replication; Virus; Viral entry; Subgenomic mRNA; RNA; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003551267,0.0002216044,0.0006248617,0.0002152436,0.00004865278,0.00001404539,0.0001732531,0.0002597339,0.00005704329],"category_scores_gemma":[0.0003212534,0.0002025749,0.0001095051,0.0003381121,0.0001278193,0.000437458,0.00009493328,0.0002692526,0.0001286331],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001072123,"about_ca_system_score_gemma":0.0001982621,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00127187,"about_ca_topic_score_gemma":0.0005847778,"domain_scores_codex":[0.9980552,0.0001577274,0.0006954397,0.0004528653,0.000299204,0.0003396165],"domain_scores_gemma":[0.998071,0.00005315143,0.0003390883,0.001068321,0.0002589971,0.0002094951],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003039062,0.002724729,0.3171507,0.001261016,0.0004017085,0.0002746608,0.01461521,0.00004182773,0.5741683,0.006438811,0.04018196,0.03970204],"study_design_scores_gemma":[0.0138927,0.002684491,0.03870056,0.0003454457,0.0006010208,0.002824735,0.0003315358,0.008827564,0.6130453,0.001687008,0.3163712,0.0006884379],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9904707,0.0005959778,0.0007203715,0.001640838,0.0006353416,0.0004945712,0.00002929934,0.0001244682,0.005288431],"genre_scores_gemma":[0.9966498,0.000656581,0.0005743883,0.001182458,0.0002628036,0.0000629554,0.0001328927,0.00003360872,0.0004445189],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2784502,"threshold_uncertainty_score":0.8260764,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06179611386645382,"score_gpt":0.3078701790030308,"score_spread":0.246074065136577,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}