{"id":"W2153364107","doi":"10.1534/genetics.105.042911","title":"<i>De Novo</i> GMP Synthesis Is Required for Axon Guidance in Drosophila","year":2005,"lang":"en","type":"article","venue":"Genetics","topic":"Axon Guidance and Neuronal Signaling","field":"Neuroscience","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Biology; De novo synthesis; Guanine; Nucleotide; Visual phototransduction; Guanine nucleotide exchange factor; Gene; Cell biology; Genetics; Biochemistry; Retinal; Signal transduction; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002071972,0.0001550472,0.0001719134,0.00006540698,0.0001067798,0.00004234571,0.0003439112,0.00008445958,0.0000403606],"category_scores_gemma":[0.0004165674,0.0001660092,0.00007865633,0.0001935147,0.00006879316,0.00008363436,0.00005731908,0.0001002848,0.00007493699],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006508348,"about_ca_system_score_gemma":0.00005865521,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002056331,"about_ca_topic_score_gemma":0.000008555883,"domain_scores_codex":[0.9984921,0.00005521909,0.0003219011,0.0004378255,0.0002200729,0.000472892],"domain_scores_gemma":[0.9991395,0.0003658312,0.00008952606,0.0002951268,0.00002640208,0.0000835811],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004764541,0.00006319079,0.0007118939,0.00002070815,0.000001384166,0.00001151417,0.0001723169,0.001166731,0.981397,0.0003757962,0.001751442,0.01428038],"study_design_scores_gemma":[0.0002846579,0.0000545142,0.000456365,0.00003766429,0.000007408821,0.00001503253,0.000007456151,0.003622378,0.9097528,0.0009106187,0.08466858,0.0001824923],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9916236,0.0005929535,0.002048529,0.003355336,0.0001804106,0.0003611145,0.00005218131,0.00006275185,0.001723151],"genre_scores_gemma":[0.9864638,0.0002480295,0.00404578,0.008284397,0.0004400385,0.00009017482,4.836609e-7,0.00003557872,0.0003917546],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08291715,"threshold_uncertainty_score":0.676966,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05713548615168407,"score_gpt":0.2965121695046919,"score_spread":0.2393766833530079,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}