{"id":"W2153415726","doi":"10.1093/cvr/cvp392","title":"Desensitization of vascular endothelin receptors by G protein-coupled receptor kinase 2","year":2009,"lang":"en","type":"letter","venue":"Cardiovascular Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Desensitization (medicine); Receptor; Endothelin receptor; Homologous desensitization; Internal medicine; Medicine; Endocrinology; Pharmacology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001009826,0.0002210871,0.0001904611,0.00009396965,0.0001313021,0.0002140916,0.0001966914,0.0002958023,0.005265696],"category_scores_gemma":[0.0001345318,0.0001033112,0.000291846,0.000102131,0.0001227374,0.0002616604,0.0001583971,0.0006806844,0.001171967],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000220075,"about_ca_system_score_gemma":0.0001042102,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003117842,"about_ca_topic_score_gemma":0.0003305798,"domain_scores_codex":[0.9999076,0.00001539255,0.000006505339,0.00002206053,0.00001972618,0.00002866619],"domain_scores_gemma":[0.9999713,0.000007336314,0.00000639179,0.00000381708,0.000004343154,0.000006856194],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006500823,0.0001152213,0.0003063102,0.0002020984,0.0000150695,0.0005108711,0.0000372275,0.0001986354,0.9821247,0.001147407,0.0009164859,0.01377583],"study_design_scores_gemma":[0.0005546807,0.002485832,0.07155792,0.00008448966,0.00007286459,0.004814023,0.0002110388,0.00432916,0.8141598,0.002395399,0.09928315,0.00005165458],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9202484,0.05221121,0.005787319,0.001049764,0.0009622672,0.0001595119,0.0008857316,0.0002475687,0.01844813],"genre_scores_gemma":[0.9596764,0.01687266,0.00166162,0.0007803783,0.0001533377,0.0001073514,0.0008669704,0.00002756949,0.01985367],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005265696,"threshold_uncertainty_score":0.01761544,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02367327023235508,"score_gpt":0.272311964590481,"score_spread":0.2486386943581259,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}