{"id":"W2153450922","doi":"10.1210/en.2005-0365","title":"Hypoxia-Inducible Factor-1-Mediated Activation of Stanniocalcin-1 in Human Cancer Cells","year":2005,"lang":"en","type":"article","venue":"Endocrinology","topic":"Physiological and biochemical adaptations","field":"Environmental Science","cited_by":117,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Centre National d’Etudes Spatiales","keywords":"Endocrinology; Internal medicine; Biology; Gene expression; Cancer cell; Hypoxia (environmental); Hypoxia-inducible factors; Cell culture; Regulation of gene expression; Cancer; Cancer research; Gene; Chemistry; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00001786881,0.0000793039,0.0001280883,0.0000304253,0.00003019921,0.000001898909,0.0001338951,0.00005615704,0.003068007],"category_scores_gemma":[0.00002119913,0.00006291149,0.00002756686,0.0001750522,0.000144515,0.00007917253,0.00008597533,0.0001231225,0.0001250411],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001000942,"about_ca_system_score_gemma":0.000005958291,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007040104,"about_ca_topic_score_gemma":0.0001582749,"domain_scores_codex":[0.9992451,0.00003165061,0.0001828879,0.0002041391,0.00009205259,0.0002441799],"domain_scores_gemma":[0.9997354,0.0000546698,0.00005968809,0.0001048581,0.000005307753,0.00004011778],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000007763968,0.0001252063,0.004811713,0.000001672944,0.000002953346,7.857917e-7,0.0000581202,0.0009605825,0.9901225,0.0001265691,0.0003323385,0.003449785],"study_design_scores_gemma":[0.0002145901,0.00004641811,0.1708644,0.000003230545,0.000001324079,2.723849e-7,0.00001648471,0.0001079068,0.8252445,0.0004820475,0.002948541,0.00007028463],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964573,0.00001692156,0.00003007206,0.0004680653,0.00002786749,0.00008714095,0.00001567802,0.00002118687,0.002875732],"genre_scores_gemma":[0.999272,0.00001977822,0.0001887741,0.0002013602,0.00003039897,0.00001933436,0.00001079824,0.000003738798,0.0002537752],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1660527,"threshold_uncertainty_score":0.9978433,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03029524751783387,"score_gpt":0.2763302839862794,"score_spread":0.2460350364684455,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}