{"id":"W2153515433","doi":"10.1128/ec.00024-09","title":"Endoplasmic Reticulum-Associated Secretory Proteins Sec20p, Sec39p, and Dsl1p Are Involved in Peroxisome Biogenesis","year":2009,"lang":"en","type":"article","venue":"Eukaryotic Cell","topic":"Peroxisome Proliferator-Activated Receptors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Fondation pour la Recherche Médicale; Howard Hughes Medical Institute","keywords":"Peroxisome; Endoplasmic reticulum; Biology; Cell biology; Secretory pathway; Biogenesis; Secretory protein; Calnexin; Green fluorescent protein; Golgi apparatus; Saccharomyces cerevisiae; Protein targeting; Organelle biogenesis; Unfolded protein response; Peroxisomal targeting signal; Membrane protein; Biochemistry; Yeast; Secretion; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002813319,0.0003946892,0.0003856443,0.0001740025,0.0001146709,0.0000487673,0.0002636554,0.0004498308,0.00006912864],"category_scores_gemma":[0.0001492088,0.0004009549,0.0001145041,0.0003263343,0.0001255449,0.00001525552,0.0001232774,0.0002991671,0.00002595819],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009807292,"about_ca_system_score_gemma":0.0001358429,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005025619,"about_ca_topic_score_gemma":0.000151494,"domain_scores_codex":[0.9978179,0.000219449,0.0004000799,0.0007301908,0.0002416407,0.0005907587],"domain_scores_gemma":[0.9990233,0.00002304126,0.0001993472,0.0004434701,0.00008451784,0.0002263319],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009597668,0.00034514,0.1906084,0.00004165953,0.00003798289,0.00002695775,0.0001521852,0.00003218522,0.8077334,0.000004966518,0.0006638466,0.000257314],"study_design_scores_gemma":[0.001569926,0.0005005415,0.1368924,0.000066271,0.00002560462,0.00001242418,0.0002607744,0.0001421111,0.8594643,0.00005590942,0.0005136912,0.0004960598],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962071,0.001881925,0.00002611041,0.0002771618,0.0001622646,0.0005978947,0.00004521939,0.00006169179,0.0007406734],"genre_scores_gemma":[0.9976839,0.0004881791,0.0002891167,0.0004989298,0.0001473217,0.0000419522,0.0001881074,0.00005213337,0.000610406],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05371599,"threshold_uncertainty_score":0.9998443,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00670973386773305,"score_gpt":0.2017119462435542,"score_spread":0.1950022123758212,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}