{"id":"W2153515433","doi":"10.1128/ec.00024-09","title":"Endoplasmic Reticulum-Associated Secretory Proteins Sec20p, Sec39p, and Dsl1p Are Involved in Peroxisome Biogenesis","year":2009,"lang":"en","type":"article","venue":"Eukaryotic Cell","topic":"Peroxisome Proliferator-Activated Receptors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Fondation pour la Recherche Médicale; Howard Hughes Medical Institute","keywords":"Peroxisome; Endoplasmic reticulum; Biology; Cell biology; Secretory pathway; Biogenesis; Secretory protein; Calnexin; Green fluorescent protein; Golgi apparatus; Saccharomyces cerevisiae; Protein targeting; Organelle biogenesis; Unfolded protein response; Peroxisomal targeting signal; Membrane protein; Biochemistry; Yeast; Secretion; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001022202,0.0006612987,0.0002829967,0.0002462615,0.0002472647,0.0004008269,0.0001779086,0.0002681334,0.001948384],"category_scores_gemma":[0.0001264243,0.0001475922,0.0002499271,0.0003171754,0.0002407923,0.0003169496,0.0003495456,0.0003626245,0.001380035],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004638205,"about_ca_system_score_gemma":0.0002159558,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004716529,"about_ca_topic_score_gemma":0.0004280623,"domain_scores_codex":[0.9999162,0.00001034721,0.000008410791,0.0000262523,0.00002704415,0.00001172371],"domain_scores_gemma":[0.9998509,0.00001396845,0.00005699319,0.00001456527,0.00003126536,0.00003236451],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003372164,0.000006964224,0.0006842374,0.00004840768,0.000003378706,0.0001355795,0.00001640422,0.00003820288,0.9971993,0.000082259,0.00003930978,0.001712218],"study_design_scores_gemma":[0.00000690663,0.0000550857,0.0132943,0.000008299164,0.00001274006,0.0009270163,0.00005983564,0.0006293004,0.9790121,0.0000940863,0.00589438,0.00000604913],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9882432,0.002919802,0.005529238,0.0001962116,0.00001958722,0.00001987919,0.001381443,0.0001675881,0.001523099],"genre_scores_gemma":[0.9838113,0.003128742,0.003449363,0.00007157139,0.00001130708,0.00002548984,0.003670019,0.00005127793,0.005780939],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001948384,"threshold_uncertainty_score":0.006518006,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00670973386773305,"score_gpt":0.2017119462435542,"score_spread":0.1950022123758212,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}