{"id":"W2153515923","doi":"10.1128/jvi.00933-14","title":"Interaction of Adenovirus Type 5 E4orf4 with the Nuclear Pore Subunit Nup205 Is Required for Proper Viral Gene Expression","year":2014,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Canadian Institutes of Health Research","keywords":"Biology; Gene knockdown; Protein phosphatase 2; Molecular biology; Viral structural protein; Mutant; Immunoprecipitation; Nuclear protein; Gene expression; Gene; Viral replication; Protein subunit; Cell biology; Virus; Viral entry; Virology; Genetics; Transcription factor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004945281,0.0001057579,0.0001914271,0.00006635875,0.00006915574,0.00001083377,0.0002883597,0.0001361746,0.00007130786],"category_scores_gemma":[0.00007303229,0.0000615977,0.00009160651,0.00005729424,0.0001385841,0.00001013673,0.0000561036,0.000180613,0.000004514415],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001349952,"about_ca_system_score_gemma":0.00007651334,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003069771,"about_ca_topic_score_gemma":0.00001041083,"domain_scores_codex":[0.9990691,0.0001875676,0.0002587255,0.000141015,0.0001621396,0.0001814497],"domain_scores_gemma":[0.9989887,0.00003066937,0.0003348673,0.0002632668,0.0003286172,0.00005386047],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01779315,0.00007101115,0.0001476365,0.00001146993,0.00009128739,0.000002062468,0.000115585,0.000116096,0.9755983,0.000009120521,0.003928314,0.002115907],"study_design_scores_gemma":[0.001249521,0.01793222,0.0002448335,0.0000157831,0.00003212842,0.0001258603,0.00007720504,0.0001253013,0.9306912,0.0000555012,0.04937018,0.00008021602],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973382,0.0003098754,0.0007009294,0.001279062,0.0001109911,0.0001526839,0.000005099489,0.000002177353,0.0001009819],"genre_scores_gemma":[0.9978706,0.0001271967,0.0006156892,0.0007889142,0.0003586381,0.000004036125,0.000008746902,0.00002856093,0.0001976252],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04544186,"threshold_uncertainty_score":0.2511881,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0216385802924463,"score_gpt":0.3034121239089845,"score_spread":0.2817735436165382,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}