{"id":"W2153515923","doi":"10.1128/jvi.00933-14","title":"Interaction of Adenovirus Type 5 E4orf4 with the Nuclear Pore Subunit Nup205 Is Required for Proper Viral Gene Expression","year":2014,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Canadian Institutes of Health Research","keywords":"Biology; Gene knockdown; Protein phosphatase 2; Molecular biology; Viral structural protein; Mutant; Immunoprecipitation; Nuclear protein; Gene expression; Gene; Viral replication; Protein subunit; Cell biology; Virus; Viral entry; Virology; Genetics; Transcription factor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000143567,0.0004840963,0.0002226975,0.000131389,0.0003060849,0.0003053198,0.0003238385,0.0003643078,0.001876935],"category_scores_gemma":[0.0001797015,0.0001873737,0.0003401418,0.00009180311,0.0003502012,0.0001781631,0.0003175757,0.0004006619,0.001001036],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006777346,"about_ca_system_score_gemma":0.0002978718,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007262899,"about_ca_topic_score_gemma":0.0009763002,"domain_scores_codex":[0.9998156,0.00003203371,0.00002410771,0.00003845937,0.00004661024,0.00004316399],"domain_scores_gemma":[0.9997666,0.00004827009,0.00007556456,0.00002997392,0.00001836436,0.00006114096],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009669139,0.00001535086,0.000336234,0.00002857756,0.000003975394,0.00009787521,0.000005569297,0.00003735423,0.9987935,0.00004751986,0.00003570625,0.0005016925],"study_design_scores_gemma":[0.00001244983,0.0001294802,0.01028485,0.000005524502,0.00001316145,0.0006280164,0.00003559182,0.00104497,0.9847313,0.00004665081,0.003062598,0.000005360442],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946616,0.0008423708,0.002757087,0.00009353983,0.00004717017,0.00002235845,0.0003766877,0.0001437406,0.001055462],"genre_scores_gemma":[0.9925587,0.0002039591,0.003690075,0.00003936031,0.00001186478,0.00003127283,0.0009263263,0.00003104072,0.002507404],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001876935,"threshold_uncertainty_score":0.006278932,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0216385802924463,"score_gpt":0.3034121239089845,"score_spread":0.2817735436165382,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}