{"id":"W2153536272","doi":"10.1111/j.1574-6968.1997.tb12788.x","title":"The glycopeptide antibiotic producer Streptomyces toyocaensis NRRL 15009 has both d-alanyl-d-alanine and d-alanyl-d-lactate ligases","year":2006,"lang":"en","type":"article","venue":"FEMS Microbiology Letters","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Medical Research Council; Natural Sciences and Engineering Research Council of Canada; Medical Research Council Canada","keywords":"Glycopeptide; Peptidoglycan; Glycopeptide antibiotic; Biochemistry; Antibiotics; Depsipeptide; Biology; Enzyme; Streptomyces; DNA ligase; Dipeptidase; Vancomycin; Microbiology; Bacteria; Genetics; Staphylococcus aureus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008331501,0.0004480204,0.0003548268,0.0001582932,0.00009956696,0.0004164123,0.0001526417,0.0001892459,0.0005267813],"category_scores_gemma":[0.0003209194,0.0001272876,0.0002170996,0.0002351468,0.0001564662,0.0001777724,0.0002301492,0.0003003196,0.0004222158],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002593701,"about_ca_system_score_gemma":0.0001874813,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001508877,"about_ca_topic_score_gemma":0.001231481,"domain_scores_codex":[0.9998055,0.00003002155,0.00003229038,0.00004293811,0.00006532217,0.00002389745],"domain_scores_gemma":[0.9997877,0.00003303099,0.000053835,0.0000300414,0.00002891603,0.00006636903],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000466297,0.000007844941,0.0006817387,0.00001508498,0.000002315624,0.00005578907,0.000007491995,0.0000273478,0.998312,0.00001691885,0.000007663784,0.0008191791],"study_design_scores_gemma":[0.00001136041,0.0002356645,0.0121958,0.000006266784,0.00001788679,0.001114439,0.00006293115,0.0006446479,0.983502,0.00004404671,0.00215751,0.000007377797],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954396,0.0004516378,0.002884929,0.00005702024,0.000009749628,0.00001333969,0.0003496339,0.00005714681,0.0007369884],"genre_scores_gemma":[0.9933223,0.0002196352,0.003185544,0.00002088353,0.00000391762,0.00001379935,0.001744875,0.00001967045,0.001469431],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001508877,"threshold_uncertainty_score":0.0030002,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007411486219019658,"score_gpt":0.1861444218418908,"score_spread":0.1787329356228711,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}