{"id":"W2153563181","doi":"10.1095/biolreprod.110.085480","title":"Side-by-Side Comparison of Five Commercial Media Systems in a Mouse Model: Suboptimal In Vitro Culture Interferes with Imprint Maintenance1","year":2010,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"Genetic Syndromes and Imprinting","field":"Biochemistry, Genetics and Molecular Biology","cited_by":208,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children’s Health Research Institute; Western University","funders":"Institute of Gender and Health; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; March of Dimes Foundation","keywords":"Genomic imprinting; Biology; Embryo culture; Imprinting (psychology); Blastocyst; Embryo; Epigenetics; DNA methylation; Andrology; Genetics; In vivo; Reproductive technology; Embryogenesis; Cell biology; Gene expression; Gene; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003035671,0.0001393419,0.0003330585,0.00007479182,0.00001669623,0.000004254123,0.0001503367,0.0002405964,0.000001177127],"category_scores_gemma":[0.0001674393,0.0001129895,0.00004411391,0.00007691205,0.0002030644,0.000004458512,0.00008957564,0.0002190711,4.219837e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000121002,"about_ca_system_score_gemma":0.00004041405,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006355584,"about_ca_topic_score_gemma":0.0004597489,"domain_scores_codex":[0.998798,0.0000651606,0.0004166857,0.0004559415,0.00005951077,0.0002047268],"domain_scores_gemma":[0.9992161,0.000008961895,0.0002454307,0.0003811343,0.0001178054,0.0000305064],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002171977,0.0001116172,0.02476896,0.00003117495,0.00001972888,1.886249e-7,0.0003767624,0.001491032,0.9676161,0.00002515004,0.00005752153,0.005284552],"study_design_scores_gemma":[0.0006303265,0.0003524241,0.008135062,0.00002290962,0.000006835802,0.00002326887,0.0006495455,0.00171431,0.9878423,0.00002806393,0.0004607218,0.0001341981],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970838,0.001113107,0.001114765,0.00008584007,0.0002513007,0.0002689468,0.00002470483,0.000005726877,0.00005174814],"genre_scores_gemma":[0.9971758,0.00009134165,0.002421037,0.000005430736,0.00009108241,0.00002886582,0.00009017564,0.00001244845,0.00008389312],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02022622,"threshold_uncertainty_score":0.4607576,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01211776823112185,"score_gpt":0.2601739981159074,"score_spread":0.2480562298847856,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}