{"id":"W2153612421","doi":"10.1016/j.taap.2010.07.016","title":"Evaluation of cytotoxicity and oxidative DNA damaging effects of di(2-ethylhexyl)-phthalate (DEHP) and mono(2-ethylhexyl)-phthalate (MEHP) on MA-10 Leydig cells and protection by selenium","year":2010,"lang":"en","type":"article","venue":"Toxicology and Applied Pharmacology","topic":"Effects and risks of endocrine disrupting chemicals","field":"Environmental Science","cited_by":203,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Erasmus+; Indigenous and Northern Affairs Canada; International Union of Toxicology","keywords":"Phthalate; Cytotoxicity; Selenium; Chemistry; Leydig cell; Oxidative phosphorylation; Endocrinology; Biochemistry; Biology; In vitro; Organic chemistry; Hormone","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003381656,0.0004771308,0.000314446,0.000438632,0.0003303949,0.0001694638,0.0003108946,0.00047896,0.001646886],"category_scores_gemma":[0.0002429065,0.0002462876,0.000521604,0.0004349689,0.0002989415,0.0003174395,0.0002541159,0.0004130114,0.0002816761],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000180574,"about_ca_system_score_gemma":0.0003502699,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00142244,"about_ca_topic_score_gemma":0.001617947,"domain_scores_codex":[0.999732,0.00007417426,0.00005247747,0.00003456635,0.00005887548,0.00004798604],"domain_scores_gemma":[0.999671,0.0001157515,0.00004031769,0.00005622628,0.00007829105,0.00003845637],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007963416,0.000123725,0.001883879,0.0001195449,0.00004068927,0.0002068848,0.0001323891,0.0002288419,0.9940522,0.0001261986,0.00003469405,0.002254621],"study_design_scores_gemma":[0.0000265742,0.001469173,0.008414151,0.000005384725,0.00005629558,0.0002250552,0.00008880167,0.0003026783,0.98858,0.00004895272,0.0007766786,0.000006297783],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959673,0.001452338,0.001137904,0.00004964299,0.00003006466,0.00002504301,0.0003055986,0.00001897736,0.001013265],"genre_scores_gemma":[0.9929249,0.001806262,0.001322266,0.00003808838,0.0000147721,0.00006742187,0.0007383982,0.000006096344,0.003081757],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001646886,"threshold_uncertainty_score":0.005509377,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01070649344924007,"score_gpt":0.3172707596189935,"score_spread":0.3065642661697535,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}