{"id":"W2153621410","doi":"10.1016/s0140-6736(09)61297-6","title":"Efficacy and safety of a modified killed-whole-cell oral cholera vaccine in India: an interim analysis of a cluster-randomised, double-blind, placebo-controlled trial","year":2009,"lang":"en","type":"article","venue":"The Lancet","topic":"Vibrio bacteria research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":248,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"Styrelsen för Internationellt Utvecklingssamarbete; Bill and Melinda Gates Foundation","keywords":"Cholera vaccine; Medicine; Cholera; Placebo; Interim analysis; Cluster randomised controlled trial; Population; Vaccination; Clinical endpoint; Vaccine trial; Adverse effect; Internal medicine; Pediatrics; Randomized controlled trial; Immunology; Virology; Vibrio cholerae; Environmental health; Alternative medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001020977,0.0001752593,0.001161065,0.0001751681,0.00004190376,0.0000217583,0.0003416978,0.0001089558,0.00001022069],"category_scores_gemma":[0.0001583239,0.0001150683,0.000163938,0.0003169311,0.00007456373,0.000007413381,0.0001423486,0.0001434711,4.229853e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001241429,"about_ca_system_score_gemma":0.00004071401,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003845397,"about_ca_topic_score_gemma":0.00008192916,"domain_scores_codex":[0.9984775,0.0002984463,0.0005158364,0.0002822954,0.0001533074,0.0002726098],"domain_scores_gemma":[0.9990061,0.00009580331,0.0002292483,0.000539774,0.00007293266,0.00005614603],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8561395,0.0003180382,0.0001844047,0.00001515933,0.0006832805,0.000001305523,0.000381557,0.0004126928,0.1413607,0.000009493144,0.00008659366,0.0004072557],"study_design_scores_gemma":[0.974724,0.001482669,0.01243659,0.00001720263,0.0003582058,8.578983e-7,0.00005551894,0.0008230752,0.009780795,0.000009405524,0.0001833724,0.0001283206],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964039,0.0002914078,0.00007318502,0.0006514517,0.00003507547,0.001923955,0.00004718143,0.000005823641,0.0005679803],"genre_scores_gemma":[0.9990453,0.0002678783,0.00008819746,0.0001233517,0.0001799339,0.0000858812,0.0001209866,0.000008874556,0.00007965337],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1315799,"threshold_uncertainty_score":0.4692349,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03058615346666061,"score_gpt":0.3266725294714068,"score_spread":0.2960863760047462,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}