{"id":"W2153690977","doi":"10.1128/iai.71.3.1396-1404.2003","title":"Enterohemorrhagic<i>Escherichia coli</i>O157:H7 Disrupts Stat1-Mediated Gamma Interferon Signal Transduction in Epithelial Cells","year":2003,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; McMaster University; SickKids Foundation; Hospital for Sick Children","funders":"Canadian Institutes of Health Research; Hospital for Sick Children","keywords":"Biology; Escherichia coli; Signal transduction; Interferon gamma; Microbiology; Interferon; Escherichia coli Proteins; Transduction (biophysics); Enterobacteriaceae; Cell biology; Cytokine; Virology; Immunology; Gene; Genetics; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001683526,0.0003125872,0.0002581024,0.0001602619,0.0001442826,0.0003232164,0.0002131817,0.0003452991,0.001004331],"category_scores_gemma":[0.00008048298,0.0001864349,0.0003237228,0.0001380952,0.0002560047,0.0001330161,0.0002108939,0.0005015542,0.0004776682],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000352783,"about_ca_system_score_gemma":0.0002273527,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000792017,"about_ca_topic_score_gemma":0.001187554,"domain_scores_codex":[0.9997838,0.00004195098,0.0000264468,0.00003366872,0.00004556529,0.00006855383],"domain_scores_gemma":[0.9998865,0.00002366099,0.00003542453,0.00001542092,0.00001058664,0.00002832584],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008029732,0.0000431838,0.0001041542,0.00001550858,0.000002454924,0.00004131263,0.00001236729,0.00003573623,0.999345,0.00004257617,0.00002498109,0.0002523617],"study_design_scores_gemma":[0.00002078523,0.0004139677,0.006743677,0.00001104217,0.0000101136,0.0002305879,0.00008493183,0.0009570969,0.9900963,0.00002678786,0.001399647,0.000004968861],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973515,0.0002621636,0.000861762,0.00008033004,0.00002570984,0.0000188186,0.0003853533,0.00004292865,0.0009715292],"genre_scores_gemma":[0.9948025,0.0003667926,0.001725513,0.00009436634,0.000007416211,0.00003486211,0.000992927,0.00002880125,0.001946725],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001004331,"threshold_uncertainty_score":0.003359854,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01160388796411667,"score_gpt":0.2564311103738132,"score_spread":0.2448272224096966,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}