{"id":"W2153708939","doi":"10.1128/ec.3.6.1423-1432.2004","title":"<i>KRE5</i>Gene Null Mutant Strains of<i>Candida albicans</i>Are Avirulent and Have Altered Cell Wall Composition and Hypha Formation Properties","year":2004,"lang":"en","type":"article","venue":"Eukaryotic Cell","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":83,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; National Institutes of Health","keywords":"Candida albicans; Biology; Saccharomyces cerevisiae; Mutant; Biochemistry; Corpus albicans; Cell wall; Spheroplast; Glucan; Molecular biology; Endoplasmic reticulum; Gene; Microbiology; Escherichia coli","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005150303,0.0006556691,0.0002052522,0.0004025547,0.0002151038,0.0004321832,0.0004833183,0.000291106,0.002314257],"category_scores_gemma":[0.0001039046,0.0001777485,0.0003242704,0.0002981483,0.0002253495,0.0001640775,0.0003043927,0.0005241173,0.001222582],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004431348,"about_ca_system_score_gemma":0.0002100829,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002986725,"about_ca_topic_score_gemma":0.002637247,"domain_scores_codex":[0.9998413,0.000009577777,0.00001923558,0.00003448248,0.00006206692,0.00003328736],"domain_scores_gemma":[0.999856,0.00001017949,0.00005542911,0.00002237431,0.00001842178,0.00003755142],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000508642,0.00001908019,0.0002949213,0.00002649368,0.000007264484,0.00008502966,0.000008891206,0.00004630342,0.9980027,0.000134663,0.0001298695,0.001193934],"study_design_scores_gemma":[0.00001025718,0.00007281164,0.01512897,0.00001576495,0.00002550543,0.000875513,0.00004838307,0.0008010732,0.976428,0.00004931058,0.006526096,0.0000182926],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.983915,0.001121874,0.004921158,0.0001229216,0.00004249689,0.00004265321,0.005011457,0.0006461018,0.004176421],"genre_scores_gemma":[0.9752195,0.0005196585,0.005178491,0.00009683704,0.000009422686,0.00003677539,0.01103798,0.0002562127,0.007645161],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002986725,"threshold_uncertainty_score":0.007741988,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.017677399839176,"score_gpt":0.2245135088835016,"score_spread":0.2068361090443256,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}