{"id":"W2153708939","doi":"10.1128/ec.3.6.1423-1432.2004","title":"<i>KRE5</i>Gene Null Mutant Strains of<i>Candida albicans</i>Are Avirulent and Have Altered Cell Wall Composition and Hypha Formation Properties","year":2004,"lang":"en","type":"article","venue":"Eukaryotic Cell","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":83,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; National Institutes of Health","keywords":"Candida albicans; Biology; Saccharomyces cerevisiae; Mutant; Biochemistry; Corpus albicans; Cell wall; Spheroplast; Glucan; Molecular biology; Endoplasmic reticulum; Gene; Microbiology; Escherichia coli","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001662343,0.0002071638,0.0003794859,0.00006896297,0.0001052982,0.00002641317,0.00005689742,0.00008870556,0.00003336805],"category_scores_gemma":[0.00001150375,0.000168258,0.00007194243,0.00007266475,0.0001918882,0.0001730529,0.00003989055,0.0001620649,0.00000932578],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001088447,"about_ca_system_score_gemma":0.0000842696,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002073725,"about_ca_topic_score_gemma":0.000150606,"domain_scores_codex":[0.9986985,0.0000343613,0.000411068,0.0003091428,0.0002872587,0.0002596847],"domain_scores_gemma":[0.9992824,0.00002248118,0.0001681577,0.0002610518,0.0001040728,0.0001618249],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007577375,0.0008589465,0.0642961,0.002081743,0.00003696166,0.00005966714,0.004815066,0.00006179202,0.9258868,0.00003085419,0.0001154994,0.0009987956],"study_design_scores_gemma":[0.004611948,0.0007654087,0.34358,0.0004966866,0.0002216392,0.00007701911,0.001704115,0.000699229,0.6473084,0.0001427148,0.00009779191,0.0002950107],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954709,0.001545652,0.0006278489,0.0004279947,0.0000592114,0.0006277745,0.00004589352,0.00003351306,0.00116121],"genre_scores_gemma":[0.9980049,0.000500116,0.000703226,0.0003265135,0.00005392045,0.000008436534,0.00006050281,0.00001998016,0.0003224115],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2792839,"threshold_uncertainty_score":0.6861362,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.017677399839176,"score_gpt":0.2245135088835016,"score_spread":0.2068361090443256,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}