{"id":"W2153710399","doi":"10.1111/j.1467-7652.2011.00643.x","title":"A protease activity–depleted environment for heterologous proteins migrating towards the leaf cell apoplast","year":2011,"lang":"en","type":"article","venue":"Plant Biotechnology Journal","topic":"Transgenic Plants and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":92,"is_retracted":false,"has_abstract":true,"ca_institutions":"Medicago (Canada); Université du Québec; Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Proteases; Apoplast; Nicotiana benthamiana; Biology; Protease; Biochemistry; Secretion; Cysteine protease; Cell biology; Secretory pathway; Protease inhibitor (pharmacology); Cell wall; Enzyme; Cell; Golgi apparatus; Virology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002250936,0.0001782266,0.0001403934,0.00005311314,0.0003615834,0.00002120441,0.0003955264,0.0003479785,0.00001758323],"category_scores_gemma":[0.00002749015,0.0001207457,0.0001122619,0.00004287618,0.0001626189,0.000004402507,0.0000714915,0.0003902918,0.000008339603],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001429675,"about_ca_system_score_gemma":0.00006761661,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002024528,"about_ca_topic_score_gemma":0.00003902708,"domain_scores_codex":[0.9989987,0.00004350512,0.0002254528,0.0002881309,0.00008869516,0.0003555357],"domain_scores_gemma":[0.9993895,0.00001126529,0.00019441,0.0003161385,0.00001693541,0.00007175927],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002459752,0.0001894678,0.0001670371,0.00001032957,0.00007159141,0.000009226455,0.00007424481,0.000007924473,0.9877659,0.00005398368,0.0006038139,0.0108005],"study_design_scores_gemma":[0.0006384501,0.0006533936,0.0006541807,0.000007849058,0.00003881856,0.0007796983,0.00007180339,0.000100429,0.9189042,0.0001301714,0.07784969,0.0001713446],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9309521,0.0003313145,0.06526884,0.00186566,0.00007482636,0.000968234,0.0003838084,0.0000375003,0.0001177418],"genre_scores_gemma":[0.9916112,0.0002849076,0.007397166,0.0001490771,0.0001167759,0.0002866995,0.00005431721,0.00001954561,0.00008024448],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07724587,"threshold_uncertainty_score":0.4923865,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02760978226252386,"score_gpt":0.2074693113337249,"score_spread":0.179859529071201,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}