{"id":"W2153724714","doi":"10.1128/iai.03056-14","title":"The Cpx System Regulates Virulence Gene Expression in Vibrio cholerae","year":2015,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Vibrio bacteria research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Biology; Virulence; Vibrio cholerae; Response regulator; Cholera toxin; Signal transduction; Pilus; Microbiology; Mutant; Histidine kinase; Regulation of gene expression; Cell biology; Virulence factor; Regulator; Gene; Genetics; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004420841,0.00007551983,0.00007293905,0.00002568756,0.0002183102,0.00005215263,0.00007255268,0.00006183544,0.000001102551],"category_scores_gemma":[0.0001847566,0.00005291857,0.00002065217,0.00006712323,0.00009533673,0.000008290663,0.0002038355,0.0001017411,0.000005229679],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003142972,"about_ca_system_score_gemma":0.00003171827,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003751058,"about_ca_topic_score_gemma":0.0001568117,"domain_scores_codex":[0.9993534,0.0001941786,0.0001133696,0.0001213396,0.000077633,0.0001400965],"domain_scores_gemma":[0.9995874,0.0000156285,0.0000374166,0.0002281366,0.00008019362,0.00005123789],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008616431,0.00002047413,0.01484617,0.00001280782,0.00001105063,6.239742e-7,0.0001015393,0.00001446841,0.9827242,0.00001019982,0.0003817767,0.001790552],"study_design_scores_gemma":[0.0005901728,0.0001753214,0.2339576,0.00004167728,0.000002578713,0.00002023084,0.0002818242,0.00007316085,0.7444954,0.00002473052,0.02023458,0.0001027009],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976566,0.00113338,0.0001043345,0.00006703691,0.0001544489,0.0001117325,0.00000226844,0.0000139746,0.0007562134],"genre_scores_gemma":[0.9986493,0.001014501,0.0000402449,0.00001755931,0.00006642553,0.00002433379,0.0000111325,0.000005773877,0.0001707219],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2382288,"threshold_uncertainty_score":0.2157957,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01975212405606524,"score_gpt":0.2732433100959893,"score_spread":0.253491186039924,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}