{"id":"W2153742708","doi":"10.2337/db10-1402","title":"TRP-ing Down the Path to Insulin Secretion","year":2010,"lang":"en","type":"letter","venue":"Diabetes","topic":"Ion Channels and Receptors","field":"Neuroscience","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Exocytosis; Depolarization; Transient receptor potential channel; Intracellular; Insulin; Cell biology; TRPC; Secretion; Ion channel; Biology; Chemistry; Internal medicine; Endocrinology; Receptor; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0001937987,0.0002495183,0.000224073,0.0001072352,0.0002711119,0.0001586635,0.000551984,0.0007647897,0.0002583331],"category_scores_gemma":[0.0004234282,0.0001497483,0.0001306243,0.0002391566,0.0001029777,0.00006504907,0.0001269452,0.00243591,0.000678181],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002212108,"about_ca_system_score_gemma":0.00002867674,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001206981,"about_ca_topic_score_gemma":0.000001128509,"domain_scores_codex":[0.9983231,0.0001467068,0.0001995593,0.0004779291,0.0003761539,0.0004765872],"domain_scores_gemma":[0.9991078,0.0003802579,0.0001160925,0.0003040623,0.00003428196,0.00005749194],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000001211382,0.000009307149,0.00002027038,0.00004661144,0.000003390768,0.000009535557,0.0003469902,0.000004188078,0.1911249,0.00002912382,0.804634,0.003770527],"study_design_scores_gemma":[0.00005429672,0.00003433539,0.00001974596,0.00005596859,0.000008090987,7.911611e-7,0.000007140129,0.0001118624,0.2348224,0.0002479065,0.7644314,0.0002061135],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.3669091,0.00005285202,0.00001426,0.6251529,0.006005734,0.0004364857,0.0000886944,0.0001269614,0.001212955],"genre_scores_gemma":[0.1903071,0.00003652115,0.00003180508,0.799283,0.0074861,0.00009016461,0.0000544775,0.00005972474,0.002651122],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.1766021,"threshold_uncertainty_score":0.9998655,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01779065789807555,"score_gpt":0.2325999824213367,"score_spread":0.2148093245232611,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}