{"id":"W2153747938","doi":"10.1002/hep.21440","title":"Impact of disease severity on outcome of antiviral therapy for chronic hepatitis C: Lessons from the HALT-C trial","year":2006,"lang":"en","type":"article","venue":"Hepatology","topic":"Hepatitis C virus research","field":"Medicine","cited_by":160,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute on Minority Health and Health Disparities; National Center for Research Resources; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Allergy and Infectious Diseases; Saint Louis University; National Cancer Institute; National Institutes of Health; Valeant Pharmaceuticals International; Gilead Sciences; Virginia Commonwealth University; University of Colorado School of Medicine, Anschutz Medical Campus; University of Connecticut; University of Southern California; Massachusetts General Hospital; GlaxoSmithKline; Bristol-Myers Squibb","keywords":"Medicine; Cirrhosis; Internal medicine; Gastroenterology; Hepatitis C; Ribavirin; Fibrosis; Liver disease; Platelet; Hepatology; Hepatitis C virus; Immunology; Virus","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002775453,0.0001781397,0.0006897136,0.0000948281,0.00007285679,0.00000630623,0.0002014966,0.000138059,0.0002673929],"category_scores_gemma":[0.0003994383,0.0001148881,0.0004498085,0.0001589816,0.0003529609,0.00004049045,0.00004151473,0.0002182272,0.00001646817],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001817754,"about_ca_system_score_gemma":0.0006841159,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.03087573,"about_ca_topic_score_gemma":0.00421549,"domain_scores_codex":[0.998215,0.0002720602,0.0005204133,0.0002900262,0.0003162143,0.0003862599],"domain_scores_gemma":[0.9981731,0.0007978524,0.0001886474,0.0005955019,0.0001489683,0.00009599354],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.02360677,0.0005828352,0.9607583,0.00003910111,0.0001408471,0.0000236425,0.00003726426,0.000002388716,0.0008472269,0.0006795732,0.002830096,0.01045195],"study_design_scores_gemma":[0.02622621,0.00340101,0.9631713,0.00003754201,0.00006292947,0.000001463854,0.000002324071,0.002149141,0.001780933,0.0008034991,0.002250326,0.0001132985],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939181,0.0004307164,0.0001723643,0.002149247,0.0001849259,0.001474543,0.001247762,0.00002378352,0.0003986071],"genre_scores_gemma":[0.9986442,0.0003664906,0.00008316195,0.0001441073,0.0003380924,0.0001135601,0.0001924386,0.00003022248,0.00008776382],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02666024,"threshold_uncertainty_score":0.9755778,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07903497324774311,"score_gpt":0.4254449168410604,"score_spread":0.3464099435933173,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}