{"id":"W2153779542","doi":"10.3109/10715762.2012.698009","title":"Oxidative stress in growth hormone transgenic coho salmon with compressed lifespan – a model for addressing aging","year":2012,"lang":"en","type":"article","venue":"Free Radical Research","topic":"Animal Genetics and Reproduction","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Fisheries and Oceans Canada","funders":"Skogs- och Jordbrukets Forskningsråd; AGE-WELL","keywords":"Oxidative stress; Glutathione; Antioxidant; Reactive oxygen species; Transgene; Endocrinology; Internal medicine; Enzyme assay; Hormone; Ageing; Enzyme; Genetically modified mouse; Biology; Oncorhynchus; Chemistry; Fish <Actinopterygii>; Biochemistry; Fishery; Gene; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002230154,0.0002931167,0.0001854021,0.0002506136,0.0002602882,0.0001598525,0.0001970007,0.0003041377,0.000860448],"category_scores_gemma":[0.0001526919,0.0001484408,0.0002749599,0.0001582351,0.0003953375,0.0002920397,0.0002608839,0.0005983028,0.000131122],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003647601,"about_ca_system_score_gemma":0.000409578,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003382306,"about_ca_topic_score_gemma":0.006343335,"domain_scores_codex":[0.9999195,0.000009754358,0.000009100823,0.00002368514,0.00001524069,0.00002268691],"domain_scores_gemma":[0.9998106,0.00001445711,0.00005578364,0.00002402998,0.00002787535,0.00006720462],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005966594,0.000113907,0.00326898,0.00002616771,0.00001102971,0.0001033148,0.00006669453,0.00004556342,0.9945384,0.00007900927,0.00004644781,0.001103849],"study_design_scores_gemma":[0.0002769594,0.01238726,0.1513095,0.00002860808,0.000142899,0.001471425,0.001122561,0.002396835,0.826754,0.0005367697,0.00351771,0.00005546832],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989943,0.0001251507,0.0005004655,0.00005519432,0.00001521184,0.00001941963,0.0001076312,0.000008328536,0.0001742941],"genre_scores_gemma":[0.9943283,0.0004215592,0.002168335,0.000106533,0.00001093001,0.000119492,0.0003933441,0.00002221957,0.002429341],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003382306,"threshold_uncertainty_score":0.006725192,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09392749810293918,"score_gpt":0.3647419545811318,"score_spread":0.2708144564781927,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}