{"id":"W2153802149","doi":"10.2478/s11658-012-0031-6","title":"The human telomerase catalytic subunit and viral telomerase RNA reconstitute a functional telomerase complex in a cell-free system, but not in human cells","year":2012,"lang":"en","type":"article","venue":"Cellular & Molecular Biology Letters","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Canada Research Chairs; University of Toronto","funders":"Canadian Institutes of Health Research; University of Toronto; McGill University","keywords":"Telomerase; Telomerase reverse transcriptase; Telomerase RNA component; Telomere; Protein subunit; Biology; RNA; Cell biology; Reverse transcriptase; Molecular biology; Biochemistry; DNA; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008495504,0.0005351788,0.0004660595,0.0002455586,0.0001776353,0.0006782839,0.0003153924,0.0003694704,0.001378008],"category_scores_gemma":[0.0004692537,0.0002775246,0.0002878963,0.0003168157,0.0002915801,0.0003334046,0.0003620272,0.0005489102,0.0006050824],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002955866,"about_ca_system_score_gemma":0.0003223271,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009101654,"about_ca_topic_score_gemma":0.001073276,"domain_scores_codex":[0.9992692,0.0002593296,0.00007589954,0.000167265,0.0001670634,0.00006131732],"domain_scores_gemma":[0.999642,0.0001260361,0.00004230401,0.0001056068,0.00003305088,0.0000509776],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001403308,0.00005901118,0.0003134382,0.0000486602,0.00002152425,0.00006264191,0.00005016507,0.00006895974,0.9975348,0.0002050493,0.0000562214,0.001439331],"study_design_scores_gemma":[0.00003433611,0.0005298462,0.002703494,0.00001473888,0.00005268599,0.0005147856,0.00003306893,0.001089933,0.9872278,0.00006884293,0.007723585,0.000006872692],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9839961,0.006004596,0.007139214,0.0001120785,0.0001318376,0.00005672534,0.0002514893,0.0001136108,0.002194361],"genre_scores_gemma":[0.9865176,0.001189134,0.006393008,0.00007225545,0.00003915459,0.00003492187,0.001833089,0.00004907514,0.003871674],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001378008,"threshold_uncertainty_score":0.004609883,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02004593389232903,"score_gpt":0.251457975031385,"score_spread":0.231412041139056,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}