{"id":"W2153903709","doi":"10.1186/1475-2891-11-21","title":"A randomized, double blind, placebo and active comparator controlled pilot study of UP446, a novel dual pathway inhibitor anti-inflammatory agent of botanical origin","year":2012,"lang":"en","type":"article","venue":"Nutrition Journal","topic":"Inflammatory mediators and NSAID effects","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"GDI Integrated Facility Services (Canada)","funders":"","keywords":"Medicine; WOMAC; Osteoarthritis; Placebo; Internal medicine; Erythrocyte sedimentation rate; Randomized controlled trial; Rheumatology; Celecoxib; Gastroenterology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002537925,0.001445172,0.003491387,0.000706717,0.0008373273,0.0008200083,0.001350631,0.001820663,0.006446224],"category_scores_gemma":[0.001667224,0.001009008,0.001303863,0.0006699753,0.002081547,0.001238461,0.000560371,0.002461847,0.0009458078],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004015262,"about_ca_system_score_gemma":0.002172416,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007657366,"about_ca_topic_score_gemma":0.00135721,"domain_scores_codex":[0.9990502,0.0004168822,0.00008159827,0.000176746,0.0001137776,0.0001608291],"domain_scores_gemma":[0.9982864,0.0003745625,0.0003002012,0.0001688498,0.0002287926,0.000641042],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9345156,0.04896956,0.0004061142,0.0003695442,0.0002550024,0.00003615041,0.00006361341,0.0000971279,0.008869416,0.00006012713,0.0002571674,0.006100557],"study_design_scores_gemma":[0.6652124,0.3315609,0.001597774,0.00001375558,0.0002165722,0.0000247608,0.00002975481,0.0001805415,0.0007603766,0.00005154028,0.0003405914,0.00001100218],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9810123,0.00120521,0.001379627,0.0002907439,0.0004788155,0.01390108,0.0008355965,0.00008593045,0.0008108253],"genre_scores_gemma":[0.9659516,0.001991229,0.005677967,0.001020071,0.0007100441,0.02072777,0.0009330061,0.0000249362,0.002963298],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006446224,"threshold_uncertainty_score":0.02156472,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05351411199559476,"score_gpt":0.3128887389380615,"score_spread":0.2593746269424667,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}