{"id":"W2153951351","doi":"10.1086/375465","title":"Pathways to Biomedical Discovery","year":2003,"lang":"en","type":"article","venue":"Philosophy of Science","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":91,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Organism; Computational biology; Sequence (biology); Epistemology; Drug discovery; Cognitive science; Computer science; Biology; Data science; Bioinformatics; Psychology; Genetics; Philosophy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.00768239,0.0009283088,0.0008024861,0.002716521,0.002277802,0.00815616,0.001354538,0.003672811,0.01289167],"category_scores_gemma":[0.0128936,0.0005108694,0.0009797133,0.00230991,0.01681567,0.01182745,0.005174963,0.006167662,0.00353965],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004978083,"about_ca_system_score_gemma":0.005547846,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001634606,"about_ca_topic_score_gemma":0.001116899,"domain_scores_codex":[0.9956958,0.00267639,0.0001480316,0.0004454133,0.0008524059,0.0001819318],"domain_scores_gemma":[0.9918128,0.004924117,0.0004266719,0.001102702,0.001155963,0.0005776506],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.00000778164,0.0000068161,0.00005338426,0.00007197833,0.000007610824,0.00001831996,0.0001812523,0.0003207923,0.00004779437,0.9864748,0.0053512,0.007458291],"study_design_scores_gemma":[0.000007806188,0.00000524864,0.00002554418,0.00005537367,0.000002913107,0.00002217503,0.0000862023,0.0003633635,0.00006047941,0.939791,0.05957557,0.000004340185],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","genre_codex":"other","genre_gemma":"empirical","genre_scores_codex":[0.00642789,0.06290442,0.3263197,0.2271305,0.005833051,0.0003081111,0.0006355793,0.000957277,0.3694837],"genre_scores_gemma":[0.4254877,0.1128695,0.3176592,0.03788164,0.006120884,0.001233703,0.001002982,0.0007659917,0.0969784],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.9977222,"threshold_uncertainty_score":0.04312694,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0613832740454029,"score_gpt":0.2834767786016552,"score_spread":0.2220935045562523,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}