{"id":"W2153976380","doi":"10.1111/his.12883","title":"Lack of <i><scp>PRKD</scp>2</i> and <i><scp>PRKD</scp>3</i> kinase domain somatic mutations in <i><scp>PRKD</scp>1</i> wild‐type classic polymorphous low‐grade adenocarcinomas of the salivary gland","year":2015,"lang":"en","type":"article","venue":"Histopathology","topic":"Salivary Gland Tumors Diagnosis and Treatment","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network","funders":"National Cancer Institute; Susan G. Komen","keywords":"Somatic cell; Biology; Germline mutation; Genetics; Gene; Mutation; Protein kinase domain; Sanger sequencing; Mutant","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000140702,0.0002134512,0.0001340791,0.0002711295,0.0001243036,0.0002385265,0.0001749159,0.0002340994,0.002289753],"category_scores_gemma":[0.0004651601,0.000119586,0.0001591565,0.0001702827,0.0003651828,0.0001601756,0.0001713038,0.0002308406,0.0002890581],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000116927,"about_ca_system_score_gemma":0.0001278933,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003543619,"about_ca_topic_score_gemma":0.0003778859,"domain_scores_codex":[0.9998558,0.00001590033,0.00001953628,0.00004681262,0.00003913594,0.00002283417],"domain_scores_gemma":[0.9995982,0.000119217,0.0001322359,0.00006494231,0.00003505801,0.00005038455],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0004177191,0.00003461606,0.0462776,0.0001118409,0.00003378056,0.00164673,0.00007638558,0.0001176669,0.9475856,0.0001280833,0.00005459563,0.003515383],"study_design_scores_gemma":[0.00005209063,0.001121007,0.4106626,0.00002513527,0.0001219484,0.04314243,0.0003053122,0.001125853,0.5400776,0.000211171,0.003138804,0.00001607341],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980631,0.0001396365,0.0008182586,0.00001197011,0.000001991634,0.00001391109,0.0001932079,0.00002231182,0.0007355224],"genre_scores_gemma":[0.9989859,0.00005926651,0.000490788,0.000008110748,0.000001304324,0.000007796721,0.0002670328,0.000006327395,0.0001733875],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002289753,"threshold_uncertainty_score":0.007659972,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03438880371537784,"score_gpt":0.2675363007298246,"score_spread":0.2331474970144468,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}