{"id":"W2153976380","doi":"10.1111/his.12883","title":"Lack of <i><scp>PRKD</scp>2</i> and <i><scp>PRKD</scp>3</i> kinase domain somatic mutations in <i><scp>PRKD</scp>1</i> wild‐type classic polymorphous low‐grade adenocarcinomas of the salivary gland","year":2015,"lang":"en","type":"article","venue":"Histopathology","topic":"Salivary Gland Tumors Diagnosis and Treatment","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network","funders":"National Cancer Institute; Susan G. Komen","keywords":"Somatic cell; Biology; Germline mutation; Genetics; Gene; Mutation; Protein kinase domain; Sanger sequencing; Mutant","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009268348,0.0008878159,0.001940389,0.0006891498,0.0002526448,0.00003872918,0.0005695743,0.000583889,0.00001536598],"category_scores_gemma":[0.001880997,0.0007053203,0.0004117127,0.001247643,0.001359341,0.0002232139,0.0003618014,0.0007802899,0.00007852011],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004088758,"about_ca_system_score_gemma":0.0007789084,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006830433,"about_ca_topic_score_gemma":0.0003726567,"domain_scores_codex":[0.9942946,0.000830436,0.001663706,0.001134311,0.0008942986,0.001182584],"domain_scores_gemma":[0.9942153,0.002284051,0.0010186,0.001501239,0.0002956332,0.0006851949],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00007857438,0.002893749,0.9457965,0.0005853721,0.0001101338,0.002569296,0.01094411,0.00006961387,0.008662065,0.001503544,0.02658643,0.0002005413],"study_design_scores_gemma":[0.01334903,0.002240874,0.9410473,0.0007314655,0.001192258,0.003466623,0.004312838,0.000108755,0.01594744,0.005048845,0.01233536,0.0002191857],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.974768,0.01657412,0.00004148345,0.0006446029,0.001178659,0.001422651,0.0002407265,0.0001413454,0.004988387],"genre_scores_gemma":[0.9950044,0.0004938232,0.00109005,0.001432586,0.0002969932,0.0001985446,0.0002592528,0.0001617492,0.001062622],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02023636,"threshold_uncertainty_score":0.9995398,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03438880371537784,"score_gpt":0.2675363007298246,"score_spread":0.2331474970144468,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}