{"id":"W2153988016","doi":"10.1370/afm.516","title":"Randomized Controlled Trials: Do They Have External Validity for Patients With Multiple Comorbidities?","year":2006,"lang":"en","type":"article","venue":"The Annals of Family Medicine","topic":"Chronic Disease Management Strategies","field":"Medicine","cited_by":347,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Medicine; Randomized controlled trial; Inclusion and exclusion criteria; Comorbidity; Population; Physical therapy; Inclusion (mineral); MEDLINE; Internal medicine; Alternative medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007848305,0.0003348138,0.003802351,0.0001685063,0.0001044064,0.00002702195,0.0002408572,0.00005974607,0.0001210124],"category_scores_gemma":[0.00506744,0.0001422921,0.0007122815,0.00007217185,0.0006749138,0.00008437237,0.00004178916,0.0001339668,0.000003130481],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002621227,"about_ca_system_score_gemma":0.0001091061,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007773472,"about_ca_topic_score_gemma":0.00002848213,"domain_scores_codex":[0.9961992,0.0007730271,0.001464531,0.0002735145,0.000927471,0.0003622857],"domain_scores_gemma":[0.9900966,0.007472196,0.001103911,0.0005656766,0.000655928,0.0001057002],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9171426,0.001077175,0.00678669,0.0004611453,0.002112885,0.00001358053,0.0004692604,0.0001149552,0.0002567536,0.009688687,0.06083813,0.001038082],"study_design_scores_gemma":[0.9453618,0.001504386,0.03124631,0.001120569,0.003496008,0.00000147801,0.0008764311,0.000748819,0.0001400015,0.0130306,0.002273207,0.0002004144],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.952682,0.004327421,0.002374424,0.007423025,0.0004631307,0.01150553,0.000134821,0.00008994751,0.02099976],"genre_scores_gemma":[0.9955501,0.0004540157,0.0001462502,0.001144798,0.0008925241,0.0004676989,0.0001642147,0.00003407119,0.001146338],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05856492,"threshold_uncertainty_score":0.6066565,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2938779467883981,"score_gpt":0.4245742696134294,"score_spread":0.1306963228250313,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}